An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report
Abstract Background Low-grade fibromyxoid sarcoma is a rare soft tissue tumor characterized by a benign histological appearance but with a high potential for recurrence and metastasis. First described by Evans in 1987, recurrence and metastasis can occur decades after the initial diagnosis, complica...
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BMC
2025-01-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-025-05038-z |
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| author | Amr Mansour Assil Mahamid Eyal Behrbalk |
| author_facet | Amr Mansour Assil Mahamid Eyal Behrbalk |
| author_sort | Amr Mansour |
| collection | DOAJ |
| description | Abstract Background Low-grade fibromyxoid sarcoma is a rare soft tissue tumor characterized by a benign histological appearance but with a high potential for recurrence and metastasis. First described by Evans in 1987, recurrence and metastasis can occur decades after the initial diagnosis, complicating long-term management. Case presentation We report the case of an 83-year-old Jewish female patient diagnosed with low-grade fibromyxoid sarcoma in her right shoulder. The patient underwent wide resection with positive margins, followed by regular follow-ups. At 9 months postoperatively, she developed recurrence involving the right trapezius, thoracic vertebrae, ribs, and pleural cavity, a second local resection was performed. At 2 years post-surgery, the patient remains recurrence free. Conclusion Low-grade fibromyxoid sarcoma, though rare, presents a high risk for recurrence and metastasis. Long-term follow-up and vigilant monitoring are crucial, particularly in cases where positive surgical margins are involved. Surgery remains the cornerstone of treatment, but ongoing research into systemic therapies may offer new options for managing metastatic or recurrent low-grade fibromyxoid sarcoma in the future. |
| format | Article |
| id | doaj-art-c89fa4e00e4d4a4b830ac5b9ce5e2e83 |
| institution | Kabale University |
| issn | 1752-1947 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj-art-c89fa4e00e4d4a4b830ac5b9ce5e2e832025-01-26T12:35:26ZengBMCJournal of Medical Case Reports1752-19472025-01-011911410.1186/s13256-025-05038-zAn elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case reportAmr Mansour0Assil Mahamid1Eyal Behrbalk2Division of Orthopedic Surgery, Hillel Yaffe Medical CenterDivision of Orthopedic Surgery, Hillel Yaffe Medical CenterDivision of Orthopedic Surgery, Hillel Yaffe Medical CenterAbstract Background Low-grade fibromyxoid sarcoma is a rare soft tissue tumor characterized by a benign histological appearance but with a high potential for recurrence and metastasis. First described by Evans in 1987, recurrence and metastasis can occur decades after the initial diagnosis, complicating long-term management. Case presentation We report the case of an 83-year-old Jewish female patient diagnosed with low-grade fibromyxoid sarcoma in her right shoulder. The patient underwent wide resection with positive margins, followed by regular follow-ups. At 9 months postoperatively, she developed recurrence involving the right trapezius, thoracic vertebrae, ribs, and pleural cavity, a second local resection was performed. At 2 years post-surgery, the patient remains recurrence free. Conclusion Low-grade fibromyxoid sarcoma, though rare, presents a high risk for recurrence and metastasis. Long-term follow-up and vigilant monitoring are crucial, particularly in cases where positive surgical margins are involved. Surgery remains the cornerstone of treatment, but ongoing research into systemic therapies may offer new options for managing metastatic or recurrent low-grade fibromyxoid sarcoma in the future.https://doi.org/10.1186/s13256-025-05038-zLow-grade fibromyxoid sarcomaLGFMSSoft tissue tumorRecurrenceMetastasisTumor resection |
| spellingShingle | Amr Mansour Assil Mahamid Eyal Behrbalk An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report Journal of Medical Case Reports Low-grade fibromyxoid sarcoma LGFMS Soft tissue tumor Recurrence Metastasis Tumor resection |
| title | An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report |
| title_full | An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report |
| title_fullStr | An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report |
| title_full_unstemmed | An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report |
| title_short | An elderly patient with low-grade fibromyxoid sarcoma with early postoperative recurrences and metastases: a case report |
| title_sort | elderly patient with low grade fibromyxoid sarcoma with early postoperative recurrences and metastases a case report |
| topic | Low-grade fibromyxoid sarcoma LGFMS Soft tissue tumor Recurrence Metastasis Tumor resection |
| url | https://doi.org/10.1186/s13256-025-05038-z |
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