Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature

We describe a rare instance of spermatic cord metastasis in a 30-year-old male with a history of colorectal adenocarcinoma. Despite undergoing left hemi-colectomy and adjuvant chemotherapy, the patient presented 5 years later with right groin pain and swelling, accompanied by rising carcinoembryonic...

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Main Authors: Pranjal Rai, MD, Pradeep Kumar, MBBS, Joe Joseph, MD, Dhairya A. Lakhani, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325004145
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author Pranjal Rai, MD
Pradeep Kumar, MBBS
Joe Joseph, MD
Dhairya A. Lakhani, MD
author_facet Pranjal Rai, MD
Pradeep Kumar, MBBS
Joe Joseph, MD
Dhairya A. Lakhani, MD
author_sort Pranjal Rai, MD
collection DOAJ
description We describe a rare instance of spermatic cord metastasis in a 30-year-old male with a history of colorectal adenocarcinoma. Despite undergoing left hemi-colectomy and adjuvant chemotherapy, the patient presented 5 years later with right groin pain and swelling, accompanied by rising carcinoembryonic antigen (CEA) levels. Imaging and histopathological examination confirmed metastatic adenocarcinoma. The patient underwent a right sided high inguinal orchidectomy for the same followed by a course of adjuvant chemotherapy. A year later, a second recurrence was identified close to the surgical scar site, following which he underwent re-surgery followed by adjuvant chemotherapy. This case underscores the importance of long-term surveillance in colorectal cancer patients, particularly those with lymphovascular invasion (LVI), and highlights the need to consider atypical metastatic sites in follow-up assessments. Additionally, atypical clinical symptoms should be assessed cautiously as they may preclude a more insidious etiology and require a thorough assessment by the oncologist.
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spelling doaj-art-c89921cb94f248e78db0f4bf60594ea42025-08-20T03:26:38ZengElsevierRadiology Case Reports1930-04332025-08-012084004400710.1016/j.radcr.2025.04.116Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literaturePranjal Rai, MD0Pradeep Kumar, MBBS1Joe Joseph, MD2Dhairya A. Lakhani, MD3Tata Memorial Hospital, Department of Radiology, Mumbai, India; Corresponding author.Tata Memorial Hospital, Department of Radiology, Mumbai, IndiaDepartment of Neuroradiology, West Virginia University, Morgantown, WV, USADepartment of Neuroradiology, West Virginia University, Morgantown, WV, USAWe describe a rare instance of spermatic cord metastasis in a 30-year-old male with a history of colorectal adenocarcinoma. Despite undergoing left hemi-colectomy and adjuvant chemotherapy, the patient presented 5 years later with right groin pain and swelling, accompanied by rising carcinoembryonic antigen (CEA) levels. Imaging and histopathological examination confirmed metastatic adenocarcinoma. The patient underwent a right sided high inguinal orchidectomy for the same followed by a course of adjuvant chemotherapy. A year later, a second recurrence was identified close to the surgical scar site, following which he underwent re-surgery followed by adjuvant chemotherapy. This case underscores the importance of long-term surveillance in colorectal cancer patients, particularly those with lymphovascular invasion (LVI), and highlights the need to consider atypical metastatic sites in follow-up assessments. Additionally, atypical clinical symptoms should be assessed cautiously as they may preclude a more insidious etiology and require a thorough assessment by the oncologist.http://www.sciencedirect.com/science/article/pii/S1930043325004145AdenocarcinomaColorectal cancerLymphovascular invasionRecurrenceSpermatic cord
spellingShingle Pranjal Rai, MD
Pradeep Kumar, MBBS
Joe Joseph, MD
Dhairya A. Lakhani, MD
Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
Radiology Case Reports
Adenocarcinoma
Colorectal cancer
Lymphovascular invasion
Recurrence
Spermatic cord
title Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
title_full Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
title_fullStr Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
title_full_unstemmed Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
title_short Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature
title_sort spermatic cord metastasis in patient with colorectal adenocarcinoma a case report and review of literature
topic Adenocarcinoma
Colorectal cancer
Lymphovascular invasion
Recurrence
Spermatic cord
url http://www.sciencedirect.com/science/article/pii/S1930043325004145
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