Spermatic cord metastasis in patient with colorectal adenocarcinoma: A case report and review of literature

We describe a rare instance of spermatic cord metastasis in a 30-year-old male with a history of colorectal adenocarcinoma. Despite undergoing left hemi-colectomy and adjuvant chemotherapy, the patient presented 5 years later with right groin pain and swelling, accompanied by rising carcinoembryonic...

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Bibliographic Details
Main Authors: Pranjal Rai, MD, Pradeep Kumar, MBBS, Joe Joseph, MD, Dhairya A. Lakhani, MD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325004145
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Summary:We describe a rare instance of spermatic cord metastasis in a 30-year-old male with a history of colorectal adenocarcinoma. Despite undergoing left hemi-colectomy and adjuvant chemotherapy, the patient presented 5 years later with right groin pain and swelling, accompanied by rising carcinoembryonic antigen (CEA) levels. Imaging and histopathological examination confirmed metastatic adenocarcinoma. The patient underwent a right sided high inguinal orchidectomy for the same followed by a course of adjuvant chemotherapy. A year later, a second recurrence was identified close to the surgical scar site, following which he underwent re-surgery followed by adjuvant chemotherapy. This case underscores the importance of long-term surveillance in colorectal cancer patients, particularly those with lymphovascular invasion (LVI), and highlights the need to consider atypical metastatic sites in follow-up assessments. Additionally, atypical clinical symptoms should be assessed cautiously as they may preclude a more insidious etiology and require a thorough assessment by the oncologist.
ISSN:1930-0433