Dietary niacin intake and epilepsy: a cross-sectional study
This study aimed to examine the association between dietary niacin intake and the prevalence of epilepsy. We conducted a cross-sectional analysis of 14,236 participants from the National Health and Nutrition Examination Survey (NHANES) 2013–2018. Multivariable logistic regression, generalized additi...
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| Language: | English |
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Elsevier
2025-09-01
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| Series: | Epilepsy & Behavior Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589986425000747 |
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| author | Ken Ling Xinghui He Zhiquan Yang |
| author_facet | Ken Ling Xinghui He Zhiquan Yang |
| author_sort | Ken Ling |
| collection | DOAJ |
| description | This study aimed to examine the association between dietary niacin intake and the prevalence of epilepsy. We conducted a cross-sectional analysis of 14,236 participants from the National Health and Nutrition Examination Survey (NHANES) 2013–2018. Multivariable logistic regression, generalized additive models, and subgroup analyses were employed to assess the relationship. An inverse association was found between dietary niacin intake and the prevalence of epilepsy: for every 10 mg/day increase, the odds of having epilepsy were reduced by 15 % (OR = 0.85, p = 0.0266). Participants in the highest quintile of niacin intake had a significantly lower odds of epilepsy compared to those in the lowest quintile (OR = 0.45, p = 0.0187). This negative association remained consistent across groups with diverse demographic characteristics, medical conditions, and lifestyle choices. Our findings suggest a possible inverse association between dietary niacin intake and the prevalence of epilepsy. |
| format | Article |
| id | doaj-art-c8919da2871e4d6fb40f84dfaee8a002 |
| institution | Kabale University |
| issn | 2589-9864 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Epilepsy & Behavior Reports |
| spelling | doaj-art-c8919da2871e4d6fb40f84dfaee8a0022025-08-20T03:39:36ZengElsevierEpilepsy & Behavior Reports2589-98642025-09-013110081410.1016/j.ebr.2025.100814Dietary niacin intake and epilepsy: a cross-sectional studyKen Ling0Xinghui He1Zhiquan Yang2Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, ChinaCorresponding author.; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, ChinaThis study aimed to examine the association between dietary niacin intake and the prevalence of epilepsy. We conducted a cross-sectional analysis of 14,236 participants from the National Health and Nutrition Examination Survey (NHANES) 2013–2018. Multivariable logistic regression, generalized additive models, and subgroup analyses were employed to assess the relationship. An inverse association was found between dietary niacin intake and the prevalence of epilepsy: for every 10 mg/day increase, the odds of having epilepsy were reduced by 15 % (OR = 0.85, p = 0.0266). Participants in the highest quintile of niacin intake had a significantly lower odds of epilepsy compared to those in the lowest quintile (OR = 0.45, p = 0.0187). This negative association remained consistent across groups with diverse demographic characteristics, medical conditions, and lifestyle choices. Our findings suggest a possible inverse association between dietary niacin intake and the prevalence of epilepsy.http://www.sciencedirect.com/science/article/pii/S2589986425000747Cross-sectional studyAdultsDietary niacinEpilepsyNHANES |
| spellingShingle | Ken Ling Xinghui He Zhiquan Yang Dietary niacin intake and epilepsy: a cross-sectional study Epilepsy & Behavior Reports Cross-sectional study Adults Dietary niacin Epilepsy NHANES |
| title | Dietary niacin intake and epilepsy: a cross-sectional study |
| title_full | Dietary niacin intake and epilepsy: a cross-sectional study |
| title_fullStr | Dietary niacin intake and epilepsy: a cross-sectional study |
| title_full_unstemmed | Dietary niacin intake and epilepsy: a cross-sectional study |
| title_short | Dietary niacin intake and epilepsy: a cross-sectional study |
| title_sort | dietary niacin intake and epilepsy a cross sectional study |
| topic | Cross-sectional study Adults Dietary niacin Epilepsy NHANES |
| url | http://www.sciencedirect.com/science/article/pii/S2589986425000747 |
| work_keys_str_mv | AT kenling dietaryniacinintakeandepilepsyacrosssectionalstudy AT xinghuihe dietaryniacinintakeandepilepsyacrosssectionalstudy AT zhiquanyang dietaryniacinintakeandepilepsyacrosssectionalstudy |