A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report

Inherited reticulate pigmentary disorders (IRPD) are a group of rare dermatologic conditions characterized by distinct reticulate patterns of hyperpigmentation and/or hypopigmentation of the skin. These conditions are considered genodermatoses caused by genetic mutations that are often inherited in...

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Main Authors: Sonia Czyz, Fatemeh Jafarian, Karen Holfeld
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251358966
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author Sonia Czyz
Fatemeh Jafarian
Karen Holfeld
author_facet Sonia Czyz
Fatemeh Jafarian
Karen Holfeld
author_sort Sonia Czyz
collection DOAJ
description Inherited reticulate pigmentary disorders (IRPD) are a group of rare dermatologic conditions characterized by distinct reticulate patterns of hyperpigmentation and/or hypopigmentation of the skin. These conditions are considered genodermatoses caused by genetic mutations that are often inherited in affected families. IRPDs exhibit considerable phenotypic variability, ranging from having minimal or no systemic involvement to profound associations with neurocognitive, immunologic, and other organ abnormalities. Here, we discuss a rare case of dyschromatosis symmetrica hereditaria in an otherwise healthy 6-year-old boy. In this report, we aim to present the clinical manifestations of one subtype of reticulate pigmentary genodermatosis that, although uncommon in regions like Canada, immigration from other parts of the world, like Asia, highlights the need for awareness among Canadian physicians.
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spelling doaj-art-c88a7e76e3a5481287108cffcd3d96a52025-08-20T03:15:38ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-07-011310.1177/2050313X251358966A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case reportSonia Czyz0Fatemeh Jafarian1Karen Holfeld2Department of Medicine, University of Calgary, Calgary, AB, CanadaDivision of Dermatology, Department of Medicine, University of Calgary, Calgary, AB, CanadaDivision of Dermatology, College of Medicine, University of Saskatchewan, Regina, SK, CanadaInherited reticulate pigmentary disorders (IRPD) are a group of rare dermatologic conditions characterized by distinct reticulate patterns of hyperpigmentation and/or hypopigmentation of the skin. These conditions are considered genodermatoses caused by genetic mutations that are often inherited in affected families. IRPDs exhibit considerable phenotypic variability, ranging from having minimal or no systemic involvement to profound associations with neurocognitive, immunologic, and other organ abnormalities. Here, we discuss a rare case of dyschromatosis symmetrica hereditaria in an otherwise healthy 6-year-old boy. In this report, we aim to present the clinical manifestations of one subtype of reticulate pigmentary genodermatosis that, although uncommon in regions like Canada, immigration from other parts of the world, like Asia, highlights the need for awareness among Canadian physicians.https://doi.org/10.1177/2050313X251358966
spellingShingle Sonia Czyz
Fatemeh Jafarian
Karen Holfeld
A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
SAGE Open Medical Case Reports
title A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
title_full A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
title_fullStr A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
title_full_unstemmed A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
title_short A rare presentation of dyschromatosis symmetrica hereditaria in a Canadian context: A case report
title_sort rare presentation of dyschromatosis symmetrica hereditaria in a canadian context a case report
url https://doi.org/10.1177/2050313X251358966
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