Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan
Abstract Introduction. In Pakistan, women undergoing chemotherapy are usually unaware of the potential impact of the treatment on their oral health related quality of life. This study aims to assess the impact of chemotherapy on oral health related quality of life. Method. A cross-sectional study wa...
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| Format: | Article |
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Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-91533-8 |
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| author | Asad Allana Mohiba Ali Khowaja Alijaan Inayat Uzma Shamsi Yasmin Rashid Farhan Raza Khan Shafquat Rozi |
| author_facet | Asad Allana Mohiba Ali Khowaja Alijaan Inayat Uzma Shamsi Yasmin Rashid Farhan Raza Khan Shafquat Rozi |
| author_sort | Asad Allana |
| collection | DOAJ |
| description | Abstract Introduction. In Pakistan, women undergoing chemotherapy are usually unaware of the potential impact of the treatment on their oral health related quality of life. This study aims to assess the impact of chemotherapy on oral health related quality of life. Method. A cross-sectional study was conducted among 160 breast cancer (BC) patients on chemotherapy coming to Aga Khan Hospital and Jinnah Postgraduate medical center. Data collection was performed using a validated questionnaire for sociodemographic variables, types and frequency of oral hygiene measures, oral mucositis (OM) and oral health related quality of life (OHRQoL) and oral examination was performed. Data was analyzed using simple linear regression method. Results. Among these females, 119 were married, with a mean age of 47.64 ± 10.89 years. OM was present in 88, 25 used miswak/dentonic, 33 did not receive care by dentists/nurses, 15 reported moderate to severe gingival inflammation, and 85 were at stage 3 BC. OHRQoL was significantly associated with OM, women’s age, marital status, gingival status, and platelet count. Conclusion. This multi-center cross-sectional study highlights poor OHRQoL among BC patients undergoing chemotherapy. These findings highlight the need for comprehensive oral health care for these patients to improve their quality of life and treatment outcomes. Word Count: 201. |
| format | Article |
| id | doaj-art-c87fcff320dc438f903768987bc47414 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-c87fcff320dc438f903768987bc474142025-08-20T03:05:52ZengNature PortfolioScientific Reports2045-23222025-03-0115111110.1038/s41598-025-91533-8Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi PakistanAsad Allana0Mohiba Ali Khowaja1Alijaan Inayat2Uzma Shamsi3Yasmin Rashid4Farhan Raza Khan5Shafquat Rozi6Department of Community Health Sciences, Aga Khan UniversityPakistan Society of Pediatric Oncology (PSPO)Department of Community Health Sciences, Aga Khan UniversityDepartment of Community Health Sciences, Aga Khan UniversityDepartment of Oncology, Aga Khan University KarachiDepartment of Surgery, Section of Dental Surgery, Aga Khan University KarachiDepartment of Community Health Sciences, Aga Khan UniversityAbstract Introduction. In Pakistan, women undergoing chemotherapy are usually unaware of the potential impact of the treatment on their oral health related quality of life. This study aims to assess the impact of chemotherapy on oral health related quality of life. Method. A cross-sectional study was conducted among 160 breast cancer (BC) patients on chemotherapy coming to Aga Khan Hospital and Jinnah Postgraduate medical center. Data collection was performed using a validated questionnaire for sociodemographic variables, types and frequency of oral hygiene measures, oral mucositis (OM) and oral health related quality of life (OHRQoL) and oral examination was performed. Data was analyzed using simple linear regression method. Results. Among these females, 119 were married, with a mean age of 47.64 ± 10.89 years. OM was present in 88, 25 used miswak/dentonic, 33 did not receive care by dentists/nurses, 15 reported moderate to severe gingival inflammation, and 85 were at stage 3 BC. OHRQoL was significantly associated with OM, women’s age, marital status, gingival status, and platelet count. Conclusion. This multi-center cross-sectional study highlights poor OHRQoL among BC patients undergoing chemotherapy. These findings highlight the need for comprehensive oral health care for these patients to improve their quality of life and treatment outcomes. Word Count: 201.https://doi.org/10.1038/s41598-025-91533-8Breast CancerOral health and hygieneOral mucositisOral health related quality of lifeChemotherapy |
| spellingShingle | Asad Allana Mohiba Ali Khowaja Alijaan Inayat Uzma Shamsi Yasmin Rashid Farhan Raza Khan Shafquat Rozi Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan Scientific Reports Breast Cancer Oral health and hygiene Oral mucositis Oral health related quality of life Chemotherapy |
| title | Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan |
| title_full | Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan |
| title_fullStr | Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan |
| title_full_unstemmed | Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan |
| title_short | Assessing oral Health-Related quality of life in women undergoing chemotherapy for breast Cancer in Karachi Pakistan |
| title_sort | assessing oral health related quality of life in women undergoing chemotherapy for breast cancer in karachi pakistan |
| topic | Breast Cancer Oral health and hygiene Oral mucositis Oral health related quality of life Chemotherapy |
| url | https://doi.org/10.1038/s41598-025-91533-8 |
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