Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain

Objective. To describe urologists’ practice patterns when managing patients with advanced prostate cancer (PCa) in Spain. Methods. This was an observational study conducted by 120 urologists using retrospective data of advanced PCa patients attending hospitals and outpatient centers. Results. Urolog...

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Main Authors: Maria José Ribal, Juan Ignacio Martínez-Salamanca, Camilo García Freire
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2015/186740
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author Maria José Ribal
Juan Ignacio Martínez-Salamanca
Camilo García Freire
author_facet Maria José Ribal
Juan Ignacio Martínez-Salamanca
Camilo García Freire
author_sort Maria José Ribal
collection DOAJ
description Objective. To describe urologists’ practice patterns when managing patients with advanced prostate cancer (PCa) in Spain. Methods. This was an observational study conducted by 120 urologists using retrospective data of advanced PCa patients attending hospitals and outpatient centers. Results. Urologists evaluated a total of 375 patients (mean age: 75 years; ECOG 0-1: 77%; mean serum PSA levels at study entry: 50.5 ng/Ml). Approximately 50% of patients had bone metastases, and 60.6% experienced pain as the main symptom of progressive disease. Primary androgen deprivation therapy (ADT) use was 99.7%, with continuous ADT as the dominant strategy (91.9%). After failure of initial ADT, antiandrogen withdrawal was the next method most commonly used in 57% of patients. Choice of secondary hormonal treatment was made mostly by urologists (96%), who continued to monitor patients. Patient follow-up after chemotherapy and supportive care were mainly done in urology units, although responsibility was shared with medical oncologists and radiologists. Conclusion. The urologists’ attitudes towards management of PCa in the routine practice in Spain show the urologist as an integral component even when patients progress to advanced stages of the disease.
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spelling doaj-art-c87e7456a4f14c199546b962a66b97c42025-08-20T02:19:45ZengWileyProstate Cancer2090-31112090-312X2015-01-01201510.1155/2015/186740186740Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in SpainMaria José Ribal0Juan Ignacio Martínez-Salamanca1Camilo García Freire2Department of Urology, Hospital Clínic, Carrer Villarroel 170, 08036 Barcelona, SpainDepartment of Urology, Hospital Universitario Puerta de Hierro, Calle Manuel de Falla, 1, Majadahonda, 28222 Madrid, SpainDepartment of Urology, Hospital Clínico Universitario de Santiago de Compostela, Rúa da Cantaleta 9, 15706 Santiago de Compostela, SpainObjective. To describe urologists’ practice patterns when managing patients with advanced prostate cancer (PCa) in Spain. Methods. This was an observational study conducted by 120 urologists using retrospective data of advanced PCa patients attending hospitals and outpatient centers. Results. Urologists evaluated a total of 375 patients (mean age: 75 years; ECOG 0-1: 77%; mean serum PSA levels at study entry: 50.5 ng/Ml). Approximately 50% of patients had bone metastases, and 60.6% experienced pain as the main symptom of progressive disease. Primary androgen deprivation therapy (ADT) use was 99.7%, with continuous ADT as the dominant strategy (91.9%). After failure of initial ADT, antiandrogen withdrawal was the next method most commonly used in 57% of patients. Choice of secondary hormonal treatment was made mostly by urologists (96%), who continued to monitor patients. Patient follow-up after chemotherapy and supportive care were mainly done in urology units, although responsibility was shared with medical oncologists and radiologists. Conclusion. The urologists’ attitudes towards management of PCa in the routine practice in Spain show the urologist as an integral component even when patients progress to advanced stages of the disease.http://dx.doi.org/10.1155/2015/186740
spellingShingle Maria José Ribal
Juan Ignacio Martínez-Salamanca
Camilo García Freire
Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
Prostate Cancer
title Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
title_full Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
title_fullStr Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
title_full_unstemmed Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
title_short Current Patterns of Management of Advanced Prostate Cancer in Routine Clinical Practice in Spain
title_sort current patterns of management of advanced prostate cancer in routine clinical practice in spain
url http://dx.doi.org/10.1155/2015/186740
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