CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells
Abstract The malignant progression of colorectal cancer (CRC) is intimately associated with the abnormal regulation of transmembrane glycoprotein CD147. However, the molecular mechanism via the Rap1/Rap1GAP signaling axis has not been elucidated. This study, through integrated bioinformatics analysi...
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| Main Authors: | Fu Xiaoxia, Li Rui, Chen Meiru, Yuan Lu, Jin Ying |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-98266-8 |
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