Fibroblast growth factor 21 improves diabetic cardiomyopathy by inhibiting ferroptosis via ferritin pathway

Fibroblast growth factor 21 improves diabetic cardiomyopathy by inhibiting ferroptosis via ferritin pathway

Abstract Background Diabetic cardiomyopathy (DCM) is a serious complication in patients with type 2 diabetes mellitus, and its mechanisms are complex and poorly understood. Despite growing evidence suggesting that ferroptosis plays a significant role in cardiovascular disease, it has been less exten...

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Main Authors: Ruxin Wang, Xiaofang Zhang, Haowen Ye, Xian Yang, Yongting Zhao, Liangyan Wu, Han Liu, Yun Wen, Jiaxin Wang, Ying Wang, Meixin Yu, Caixia Ma, Lihong Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cardiovascular Diabetology
Subjects:
Diabetic cardiomyopathy
Ferroptosis
FGF21
Ferritin
ATF4
Type 2 diabetes mellitus
Online Access:https://doi.org/10.1186/s12933-024-02469-8
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