Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation

Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation

Abstract Background Mesenchymal stem cells (MSCs) are critical for dental tissue regeneration, yet their differentiation potential is tightly regulated by microRNAs (miRNAs). This study aimed to investigate the role of miR-615-3p in regulating odontogenic differentiation in stem cells from the apica...

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Bibliographic Details
Main Authors: Haoqing Yang, Yishu Huang, Jiaxin Song, Xiao Han, Fengning Yuan, Zhipeng Fan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
miR-615-3p
PVT1
Mitochondrial function
Odontogenic differentiation
MCSs
Online Access:https://doi.org/10.1186/s13287-025-04528-7
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