Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases

Subcutaneous fat necrosis of the newborn (SCFN) is a rare, self-limited disorder of the panniculus which appears in the first few weeks of life. SCFN generally follows an uncomplicated course. However, there are important complications for which the patient must be regularly monitored, including thr...

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Main Authors: Leire González Lara, Asunción Vicente Villa, María Mercedes Otero Rivas, Mariona Sunol Capella, Fredy Prada, María Antonia González Enseñat
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Pediatrics and Neonatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1875957214001685
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author Leire González Lara
Asunción Vicente Villa
María Mercedes Otero Rivas
Mariona Sunol Capella
Fredy Prada
María Antonia González Enseñat
author_facet Leire González Lara
Asunción Vicente Villa
María Mercedes Otero Rivas
Mariona Sunol Capella
Fredy Prada
María Antonia González Enseñat
author_sort Leire González Lara
collection DOAJ
description Subcutaneous fat necrosis of the newborn (SCFN) is a rare, self-limited disorder of the panniculus which appears in the first few weeks of life. SCFN generally follows an uncomplicated course. However, there are important complications for which the patient must be regularly monitored, including thrombocytopenia, hypoglycemia, hypertriglyceridemia, and most importantly, hypercalcemia. We report five infants with SCFN. All children were born at term. The onset of lesions was between 1 day and 20 days after birth. The back was the most frequent location. Birth hypoxia was the most frequent risk factor. Complications included hypercalcemia, hypoglycemia, and metastatic calcifications (disseminated subcutaneous calcifications, nephrocalcinosis, and myocardial calcifications). This study provides the first case of SCFN in the context of hypoxic encephalopathy and refractory septic shock that required extracorporeal membrane oxygenation (ECMO).
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issn 1875-9572
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publisher Elsevier
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series Pediatrics and Neonatology
spelling doaj-art-c866bd6b46bf4124a8dbdbe702209ff62025-08-20T03:09:54ZengElsevierPediatrics and Neonatology1875-95722017-02-01581858810.1016/j.pedneo.2014.06.010Subcutaneous Fat Necrosis of the Newborn: Report of Five CasesLeire González Lara0Asunción Vicente Villa1María Mercedes Otero Rivas2Mariona Sunol Capella3Fredy Prada4María Antonia González Enseñat5Dermatology Department, Hospital Sant Joan de Déu, Barcelona, SpainDermatology Department, Hospital Sant Joan de Déu, Barcelona, SpainDermatology Department, Hospital Sant Joan de Déu, Barcelona, SpainPathology Department, Hospital Sant Joan de Déu, Barcelona, SpainCardiology Department, Hospital Sant Joan de Déu, Barcelona, SpainDermatology Department, Hospital Sant Joan de Déu, Barcelona, SpainSubcutaneous fat necrosis of the newborn (SCFN) is a rare, self-limited disorder of the panniculus which appears in the first few weeks of life. SCFN generally follows an uncomplicated course. However, there are important complications for which the patient must be regularly monitored, including thrombocytopenia, hypoglycemia, hypertriglyceridemia, and most importantly, hypercalcemia. We report five infants with SCFN. All children were born at term. The onset of lesions was between 1 day and 20 days after birth. The back was the most frequent location. Birth hypoxia was the most frequent risk factor. Complications included hypercalcemia, hypoglycemia, and metastatic calcifications (disseminated subcutaneous calcifications, nephrocalcinosis, and myocardial calcifications). This study provides the first case of SCFN in the context of hypoxic encephalopathy and refractory septic shock that required extracorporeal membrane oxygenation (ECMO).http://www.sciencedirect.com/science/article/pii/S1875957214001685hypercalcemiametastatic calcificationsnewbornsubcutaneous fat necrosis
spellingShingle Leire González Lara
Asunción Vicente Villa
María Mercedes Otero Rivas
Mariona Sunol Capella
Fredy Prada
María Antonia González Enseñat
Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
Pediatrics and Neonatology
hypercalcemia
metastatic calcifications
newborn
subcutaneous fat necrosis
title Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
title_full Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
title_fullStr Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
title_full_unstemmed Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
title_short Subcutaneous Fat Necrosis of the Newborn: Report of Five Cases
title_sort subcutaneous fat necrosis of the newborn report of five cases
topic hypercalcemia
metastatic calcifications
newborn
subcutaneous fat necrosis
url http://www.sciencedirect.com/science/article/pii/S1875957214001685
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AT asuncionvicentevilla subcutaneousfatnecrosisofthenewbornreportoffivecases
AT mariamercedesoterorivas subcutaneousfatnecrosisofthenewbornreportoffivecases
AT marionasunolcapella subcutaneousfatnecrosisofthenewbornreportoffivecases
AT fredyprada subcutaneousfatnecrosisofthenewbornreportoffivecases
AT mariaantoniagonzalezensenat subcutaneousfatnecrosisofthenewbornreportoffivecases