Associations between arterial health and sexual function in women aged 60–64 years

Abstract Introduction Female sexual dysfunction is very common, but its determinants remain under‐investigated. Vasculogenic impairments are suggested to be related to female sexual dysfunction, but previous literature regarding the association is scarce. This study aims to study the association bet...

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Main Authors: Viivi Virkkunen, Katja Kero, Mari Koivisto, Teemu Niiranen, Olli Heinonen, Sari Stenholm, Päivi Polo‐Kantola
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Acta Obstetricia et Gynecologica Scandinavica
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Online Access:https://doi.org/10.1111/aogs.14826
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author Viivi Virkkunen
Katja Kero
Mari Koivisto
Teemu Niiranen
Olli Heinonen
Sari Stenholm
Päivi Polo‐Kantola
author_facet Viivi Virkkunen
Katja Kero
Mari Koivisto
Teemu Niiranen
Olli Heinonen
Sari Stenholm
Päivi Polo‐Kantola
author_sort Viivi Virkkunen
collection DOAJ
description Abstract Introduction Female sexual dysfunction is very common, but its determinants remain under‐investigated. Vasculogenic impairments are suggested to be related to female sexual dysfunction, but previous literature regarding the association is scarce. This study aims to study the association between arterial health and female sexual function in women in their 60s. Material and methods The sample for this cross‐sectional study comprised 117 women (aged 60–64 years) who participated in the Finnish Retirement and Aging study. Arterial health was measured according to the participants' pulse wave velocity, ankle–brachial index, blood pressure, and pulse pressure. Sexual function was measured using the Female Sexual Function Index, which resulted in a total score and six sub‐scores. Associations were examined using multivariable regression analyses, which were adjusted for age, relationship happiness, systemic menopausal hormone therapy and/or local estrogen, smoking, alcohol risk use, body mass index, and depressive symptoms. Results Higher diastolic blood pressure was associated with a higher total Female Sexual Function Index score (β = 0.24, 95% confidence interval [CI] 0.07–0.41) and with higher desire (β = 0.02, 95% CI 0.01–0.04), arousal (β = 0.04, 95% CI 0.01–0.08), lubrication (β = 0.04, 95% CI 0.002–0.08), satisfaction (β = 0.03, 95% CI 0.003–0.05), and pain (β = 0.06, 95% CI 0.02–0.10) sub‐scores. Also, higher ankle–brachial index was associated with higher satisfaction sub‐score (β = 2.10, 95% CI 0.44–3.73) and lower pulse pressure was associated with higher orgasm sub‐score (β = 0.03, 95% CI 0.0002–0.06). Other associations between ankle–brachial index and Female Sexual Function Index scores were statistically insignificant, but considering the magnitude the findings may imply clinical significance. Systolic blood pressure and pulse wave velocity were not associated with sexual function. Conclusions This study suggested a plausible association between higher diastolic blood pressure and female sexual function, but considering clinical significance our findings suggest an association between higher ankle–brachial index and good sexual function in women in their 60s.
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spelling doaj-art-c8652ecfdea24c3c8198e1564ac48a2c2025-08-20T02:09:27ZengWileyActa Obstetricia et Gynecologica Scandinavica0001-63491600-04122024-06-0110361132114110.1111/aogs.14826Associations between arterial health and sexual function in women aged 60–64 yearsViivi Virkkunen0Katja Kero1Mari Koivisto2Teemu Niiranen3Olli Heinonen4Sari Stenholm5Päivi Polo‐Kantola6Department of Obstetrics and Gynecology Turku University Hospital and University of Turku Turku FinlandDepartment of Obstetrics and Gynecology Turku University Hospital and University of Turku Turku FinlandDepartment of Biostatistics University of Turku Turku FinlandDepartment of Internal Medicine Turku University Hospital, University of Turku Turku FinlandPaavo Nurmi Center & Unit for Health and Physical Activity University of Turku Turku FinlandDepartment of Public Health Turku University Hospital, University of Turku Turku FinlandDepartment of Obstetrics and Gynecology Turku University Hospital and University of Turku Turku FinlandAbstract Introduction Female sexual dysfunction is very common, but its determinants remain under‐investigated. Vasculogenic impairments are suggested to be related to female sexual dysfunction, but previous literature regarding the association is scarce. This study aims to study the association between arterial health and female sexual function in women in their 60s. Material and methods The sample for this cross‐sectional study comprised 117 women (aged 60–64 years) who participated in the Finnish Retirement and Aging study. Arterial health was measured according to the participants' pulse wave velocity, ankle–brachial index, blood pressure, and pulse pressure. Sexual function was measured using the Female Sexual Function Index, which resulted in a total score and six sub‐scores. Associations were examined using multivariable regression analyses, which were adjusted for age, relationship happiness, systemic menopausal hormone therapy and/or local estrogen, smoking, alcohol risk use, body mass index, and depressive symptoms. Results Higher diastolic blood pressure was associated with a higher total Female Sexual Function Index score (β = 0.24, 95% confidence interval [CI] 0.07–0.41) and with higher desire (β = 0.02, 95% CI 0.01–0.04), arousal (β = 0.04, 95% CI 0.01–0.08), lubrication (β = 0.04, 95% CI 0.002–0.08), satisfaction (β = 0.03, 95% CI 0.003–0.05), and pain (β = 0.06, 95% CI 0.02–0.10) sub‐scores. Also, higher ankle–brachial index was associated with higher satisfaction sub‐score (β = 2.10, 95% CI 0.44–3.73) and lower pulse pressure was associated with higher orgasm sub‐score (β = 0.03, 95% CI 0.0002–0.06). Other associations between ankle–brachial index and Female Sexual Function Index scores were statistically insignificant, but considering the magnitude the findings may imply clinical significance. Systolic blood pressure and pulse wave velocity were not associated with sexual function. Conclusions This study suggested a plausible association between higher diastolic blood pressure and female sexual function, but considering clinical significance our findings suggest an association between higher ankle–brachial index and good sexual function in women in their 60s.https://doi.org/10.1111/aogs.14826ankle–brachial indexarterial healthblood pressurelate middle‐aged womensexual dysfunctionsexual health
spellingShingle Viivi Virkkunen
Katja Kero
Mari Koivisto
Teemu Niiranen
Olli Heinonen
Sari Stenholm
Päivi Polo‐Kantola
Associations between arterial health and sexual function in women aged 60–64 years
Acta Obstetricia et Gynecologica Scandinavica
ankle–brachial index
arterial health
blood pressure
late middle‐aged women
sexual dysfunction
sexual health
title Associations between arterial health and sexual function in women aged 60–64 years
title_full Associations between arterial health and sexual function in women aged 60–64 years
title_fullStr Associations between arterial health and sexual function in women aged 60–64 years
title_full_unstemmed Associations between arterial health and sexual function in women aged 60–64 years
title_short Associations between arterial health and sexual function in women aged 60–64 years
title_sort associations between arterial health and sexual function in women aged 60 64 years
topic ankle–brachial index
arterial health
blood pressure
late middle‐aged women
sexual dysfunction
sexual health
url https://doi.org/10.1111/aogs.14826
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