A case of Candida mediastinitis after dental extraction

Acute mediastinitis is a serious infection involving the connective mediastinal tissue in the interpleural spaces and other thoracic structures. Candida albicans mediastinitis is a rare clinical entity associated with high mortality and morbidity. We present a rare case of a previously healthy and...

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Main Authors: Parisa Badiee, Abdolvahab Alborzi, Farimah Farhoudi
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2010-07-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/1086
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author Parisa Badiee
Abdolvahab Alborzi
Farimah Farhoudi
author_facet Parisa Badiee
Abdolvahab Alborzi
Farimah Farhoudi
author_sort Parisa Badiee
collection DOAJ
description Acute mediastinitis is a serious infection involving the connective mediastinal tissue in the interpleural spaces and other thoracic structures. Candida albicans mediastinitis is a rare clinical entity associated with high mortality and morbidity. We present a rare case of a previously healthy and immunocompetent man with Candida mediastinitis due to retropharyngeal abscess after dental extraction, who presented with odynophagia and fever. Antibiotics were prescribed and surgical drainage was performed after diagnosis of mediastinitis by CT scan; however, the patient remained febrile.  The second culture obtained during irrigation of the mediastinum was positive for Candida albicans and the patient was responsive to antifungal therapy and survived. This case illustrates the need to consider a fungal cause in immunocompetent patients with mediastinitis who are not responsive to broad spectrum antibiotics and surgical drainage.
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publisher The Journal of Infection in Developing Countries
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spelling doaj-art-c86377a673ee4c238b05f1fe27a0fada2025-08-20T02:27:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802010-07-0150110.3855/jidc.1086A case of Candida mediastinitis after dental extractionParisa Badiee0Abdolvahab Alborzi1Farimah Farhoudi2Prof. Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, IranProf. Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, IranProf. Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Acute mediastinitis is a serious infection involving the connective mediastinal tissue in the interpleural spaces and other thoracic structures. Candida albicans mediastinitis is a rare clinical entity associated with high mortality and morbidity. We present a rare case of a previously healthy and immunocompetent man with Candida mediastinitis due to retropharyngeal abscess after dental extraction, who presented with odynophagia and fever. Antibiotics were prescribed and surgical drainage was performed after diagnosis of mediastinitis by CT scan; however, the patient remained febrile.  The second culture obtained during irrigation of the mediastinum was positive for Candida albicans and the patient was responsive to antifungal therapy and survived. This case illustrates the need to consider a fungal cause in immunocompetent patients with mediastinitis who are not responsive to broad spectrum antibiotics and surgical drainage. https://jidc.org/index.php/journal/article/view/1086CandidaMediastinitisOdynophagia
spellingShingle Parisa Badiee
Abdolvahab Alborzi
Farimah Farhoudi
A case of Candida mediastinitis after dental extraction
Journal of Infection in Developing Countries
Candida
Mediastinitis
Odynophagia
title A case of Candida mediastinitis after dental extraction
title_full A case of Candida mediastinitis after dental extraction
title_fullStr A case of Candida mediastinitis after dental extraction
title_full_unstemmed A case of Candida mediastinitis after dental extraction
title_short A case of Candida mediastinitis after dental extraction
title_sort case of candida mediastinitis after dental extraction
topic Candida
Mediastinitis
Odynophagia
url https://jidc.org/index.php/journal/article/view/1086
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