Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial

We conducted a six-center, prospective, randomized, open-label trial to assess whether an early standardized educational protocol provided from 42 to 48 months of age improved the progression of oral language and phonological development in children born preterm. A total of 552 children with phonolo...

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Main Authors: Aude Charollais, Vincent Laudenbach, Marie-Hélène Stumpf, Benoît Delaporte, Valérie Datin-Dorriere, Thierry Debillon, Claire De Barace, Olivier Flechelles, Marie Farmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Psychology
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1393246/full
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author Aude Charollais
Aude Charollais
Aude Charollais
Vincent Laudenbach
Vincent Laudenbach
Vincent Laudenbach
Marie-Hélène Stumpf
Marie-Hélène Stumpf
Benoît Delaporte
Benoît Delaporte
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Thierry Debillon
Thierry Debillon
Claire De Barace
Claire De Barace
Olivier Flechelles
Olivier Flechelles
Marie Farmer
Marie Farmer
author_facet Aude Charollais
Aude Charollais
Aude Charollais
Vincent Laudenbach
Vincent Laudenbach
Vincent Laudenbach
Marie-Hélène Stumpf
Marie-Hélène Stumpf
Benoît Delaporte
Benoît Delaporte
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Thierry Debillon
Thierry Debillon
Claire De Barace
Claire De Barace
Olivier Flechelles
Olivier Flechelles
Marie Farmer
Marie Farmer
author_sort Aude Charollais
collection DOAJ
description We conducted a six-center, prospective, randomized, open-label trial to assess whether an early standardized educational protocol provided from 42 to 48 months of age improved the progression of oral language and phonological development in children born preterm. A total of 552 children with phonological fragility were included in this study. The children were randomized to receive the educational protocol (guided arm, n = 87) or not (non-guided arm, n = 78). In the guided arm, the oral language development used a short “say and do” type educational protocol designed to maintain visual attention and train the developmental phonology/lexicon/morphosyntax structural links. In contrast, a conservative approach was used in the non-guided arm. A total of 70 guided and 73 non-guided children completed the study. After 6 months, the educated children showed a non-significant increase in their phonology score (p = 0.37), while the variations in the scores of the expressive lexicon (secondary endpoints) were significantly improved (p = 0.0008). We conclude that the short, standardized stimulation of the sensorimotor aspects of language in children born very preterm increased the expressive lexicon. This protocol improved the language of the premature children, especially those with minimal motor skills, with more significant improvement in the phonological scores.Clinical trial registrationclinicaltrials.gov, identifier NCT01426659
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spelling doaj-art-c85d7094a51148adad06cf433b5844112025-08-20T02:19:11ZengFrontiers Media S.A.Frontiers in Psychology1664-10782024-12-011510.3389/fpsyg.2024.13932461393246Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trialAude Charollais0Aude Charollais1Aude Charollais2Vincent Laudenbach3Vincent Laudenbach4Vincent Laudenbach5Marie-Hélène Stumpf6Marie-Hélène Stumpf7Benoît Delaporte8Benoît Delaporte9Valérie Datin-Dorriere10Valérie Datin-Dorriere11Valérie Datin-Dorriere12Thierry Debillon13Thierry Debillon14Claire De Barace15Claire De Barace16Olivier Flechelles17Olivier Flechelles18Marie Farmer19Marie Farmer20LAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Pediatric, MFME University Hospital, Fort de France Martinique, FranceResearch center on psychological functions and dysfunctions, EA7475, University of Rouen, Mont Saint-Aignan Cedex, Rouen, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Pediatric, MFME University Hospital, Fort de France Martinique, FranceResearch center on psychological functions and dysfunctions, EA7475, University of Rouen, Mont Saint-Aignan Cedex, Rouen, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceResearch center on psychological functions and dysfunctions, EA7475, University of Rouen, Mont Saint-Aignan Cedex, Rouen, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Neonatology and Neonatal intensive Care Charles Nicolle University Hospital, Rouen, Cedex, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Neonatology and Neonatal intensive Care, Jacques Monod Hospital, Le Havre Cedex, FranceService of Neonatology and Neonatal intensive Care, Côte de Nacre Caen Normandie University Hospital, Caen Cedex 09, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Neonatology and Neonatal intensive Care Charles Nicolle University Hospital, Rouen, Cedex, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceNeonatal Intensive Care Unit, Grenoble Alpes University Hospital, La Tronche, Grenoble, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceService of Pediatric, MFME University Hospital, Fort de France Martinique, FranceLAMOPRESCO research group, University Rouen Hospital, Rouen, FranceFMSS Sherbrooke University Qβc, Sherbrooke QC, CanadaWe conducted a six-center, prospective, randomized, open-label trial to assess whether an early standardized educational protocol provided from 42 to 48 months of age improved the progression of oral language and phonological development in children born preterm. A total of 552 children with phonological fragility were included in this study. The children were randomized to receive the educational protocol (guided arm, n = 87) or not (non-guided arm, n = 78). In the guided arm, the oral language development used a short “say and do” type educational protocol designed to maintain visual attention and train the developmental phonology/lexicon/morphosyntax structural links. In contrast, a conservative approach was used in the non-guided arm. A total of 70 guided and 73 non-guided children completed the study. After 6 months, the educated children showed a non-significant increase in their phonology score (p = 0.37), while the variations in the scores of the expressive lexicon (secondary endpoints) were significantly improved (p = 0.0008). We conclude that the short, standardized stimulation of the sensorimotor aspects of language in children born very preterm increased the expressive lexicon. This protocol improved the language of the premature children, especially those with minimal motor skills, with more significant improvement in the phonological scores.Clinical trial registrationclinicaltrials.gov, identifier NCT01426659https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1393246/fullprematurityoral language disorderlanguage and motor skillsschool-agechild born pretermphonology score
spellingShingle Aude Charollais
Aude Charollais
Aude Charollais
Vincent Laudenbach
Vincent Laudenbach
Vincent Laudenbach
Marie-Hélène Stumpf
Marie-Hélène Stumpf
Benoît Delaporte
Benoît Delaporte
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Valérie Datin-Dorriere
Thierry Debillon
Thierry Debillon
Claire De Barace
Claire De Barace
Olivier Flechelles
Olivier Flechelles
Marie Farmer
Marie Farmer
Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
Frontiers in Psychology
prematurity
oral language disorder
language and motor skills
school-age
child born preterm
phonology score
title Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
title_full Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
title_fullStr Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
title_full_unstemmed Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
title_short Impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility: a multicenter randomized clinical trial
title_sort impact of an early educational protocol on the oral language of children born preterm exhibiting phonological fragility a multicenter randomized clinical trial
topic prematurity
oral language disorder
language and motor skills
school-age
child born preterm
phonology score
url https://www.frontiersin.org/articles/10.3389/fpsyg.2024.1393246/full
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