Targeted Restoration of T-Cell Subsets by a Fluorinated Piperazine Derivative β-Cyclodextrin Complex in Experimental Pulmonary Inflammation

Targeted Restoration of T-Cell Subsets by a Fluorinated Piperazine Derivative β-Cyclodextrin Complex in Experimental Pulmonary Inflammation

Acute pneumonia is frequently accompanied by immune suppression, particularly affecting T-cell subsets, such as CD4<sup>+</sup>, CD4<sup>+</sup>CD25<sup>+</sup>, and CD4<sup>+</sup>CD25<sup>+</sup>FoxP3<sup>+</sup>, which are cr...

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Bibliographic Details
Main Authors: Valentina Yu, Marina Balabekova, Assel Ten, Tolganay Zharkynbek, Sulev Koks, Milana Alimova, Raushan Koizhaiganova, Meruyert Mussilim, Aigul Malmakova, Tulegen Seilkhanov, Khaidar Tassibekov
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
complex of dimethyl[(4-benzhydrylpiperazin-1-yl)(2-fluorophenyl)methyl]phosphonate with β-Cyclodextrin ((<b><i>o</i>-Fph</b>)<b>PPhβCD</b>)
Polyoxidonium (PO)
acute pneumonia
regulatory T cells
immunomodulation
Online Access:https://www.mdpi.com/1420-3049/30/13/2741
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