Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants.

<h4>Background</h4>A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional abilities including classical complement pathway inhibition, myeloperoxidase inhibition, NET inhibition and antioxidant activity. PA-dPEG24...

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Bibliographic Details
Main Authors: Pamela S Hair, Adrianne I Enos, Neel K Krishna, Kenji M Cunnion
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226875&type=printable
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