Inhibition of complement activation, myeloperoxidase, NET formation and oxidant activity by PIC1 peptide variants.
<h4>Background</h4>A product of rational molecular design, PA-dPEG24 is the lead derivative of the PIC1 family of peptides with multiple functional abilities including classical complement pathway inhibition, myeloperoxidase inhibition, NET inhibition and antioxidant activity. PA-dPEG24...
Saved in:
| Main Authors: | Pamela S Hair, Adrianne I Enos, Neel K Krishna, Kenji M Cunnion |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2019-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0226875&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Peptide inhibition of neutrophil-mediated injury after in vivo challenge with supernatant of Pseudomonas aeruginosa and immune-complexes.
by: Adrianne Enos, et al.
Published: (2021-01-01) -
Entamoeba histolytica-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities
by: Fabian Jorge-Rosas, et al.
Published: (2024-12-01) -
A Novel Paramagnetic Substrate for Detecting Myeloperoxidase Activity in Vivo
by: Mohammed S. Shazeeb, et al.
Published: (2012-09-01) -
Myeloperoxidase-Dependent LDL Modifications in Bloodstream Are Mainly Predicted by Angiotensin II, Adiponectin, and Myeloperoxidase Activity: A Cross-Sectional Study in Men
by: Karim Zouaoui Boudjeltia, et al.
Published: (2013-01-01) -
Histones in neutrophil extracellular traps (NETs) contain oxidative post-translational modifications induced by the myeloperoxidase oxidant hypochlorous acid
by: Helen Hemmling, et al.
Published: (2025-07-01)