Mathematical modelling of reoviruses in cancer cell cultures.
Oncolytic virotherapy has emerged as a potential cancer therapy, utilizing viruses to selectively target and replicate within cancer cells while preserving normal cells. In this paper, we investigate the oncolytic potential of unmodified reovirus T3wt relative to a mutated variant SV5. In animal can...
Saved in:
| Main Authors: | Arwa Abdulla Baabdulla, Francisca Cristi, Maya Shmulevitz, Thomas Hillen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0318078 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Improved oncolytic activity of a reovirus mutant that displays enhanced virus spread due to reduced cell attachment
by: Francisca Cristi, et al.
Published: (2024-06-01) -
Cell surface heparan sulfate is an attachment receptor for grass carp reovirus
by: Qian Wang, et al.
Published: (2025-03-01) -
REOVIRUS GROWTH INHIBITION BY
ROTAVIRUS FOLLOWING COINFECTION
Published: (2003-03-01) -
Mathematical modeling of microtube-driven regrowth of gliomas after local resection
by: Alexandra Shyntar, et al.
Published: (2025-01-01) -
The PARP inhibitor talazoparib synergizes with reovirus to induce cancer killing and tumour control in vivo in mouse models
by: Joan Kyula-Currie, et al.
Published: (2025-07-01)