Transcriptome-wide association study identifies genes associated with bladder cancer risk

Transcriptome-wide association study identifies genes associated with bladder cancer risk

Abstract Genome-wide association studies (GWAS) have detected several susceptibility variants for urinary bladder cancer, but how gene regulation affects disease development remains unclear. To extend GWAS findings, we conducted a transcriptome-wide association study (TWAS) using PrediXcan to predic...

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Bibliographic Details
Main Authors: Siting Li, Jiang Gui, Margaret R. Karagas, Michael N. Passarelli
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Bladder Cancer
TWAS
GWAS
Case-control
Online Access:https://doi.org/10.1038/s41598-025-85565-3
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