Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital

Background: Anemia has been identified as a potential modifiable factor influencing aggression levels in individuals with schizophrenia. Objective: To investigate the association between anemia and incidence of aggression in patients with schizophrenia in Amino Gondohutomo Psychiatric Hospital, Sem...

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Main Authors: Elly Noerhidajati, Yulia Ratna Sofa, Sri Woroasih, Intan Tri Hardini
Format: Article
Language:English
Published: Universitas Padjadjaran 2025-04-01
Series:International Journal of Integrated Health Sciences
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Online Access:https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/4029
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author Elly Noerhidajati
Yulia Ratna Sofa
Sri Woroasih
Intan Tri Hardini
author_facet Elly Noerhidajati
Yulia Ratna Sofa
Sri Woroasih
Intan Tri Hardini
author_sort Elly Noerhidajati
collection DOAJ
description Background: Anemia has been identified as a potential modifiable factor influencing aggression levels in individuals with schizophrenia. Objective: To investigate the association between anemia and incidence of aggression in patients with schizophrenia in Amino Gondohutomo Psychiatric Hospital, Semarang, Indonesia. Methods: A cross-sectional study was conducted between January 2022 and December 2023 on patients with schizophrenia in Amino Gondohutomo Psychiatric Hospital, Semarang, Indonesia. Subjects were selected using consecutive sampling technique, and individuals with affective mood disorder and lost to follow-up were excluded from the study. Data were obtained through patients’ medical records, PANSS-EC scores, and hemoglobin measuring devices. Chi-square test and logistic regression were applied for statistical analyses. Results: Of 100 participants, patients with schizophrenia presented with aggression were predominantly above 40 years old (26 patients, 81.3%), women (17 patients, 51.1%), and non-anemic (17 patients, 57.1%). Gender and anemia were significantly associated with aggression in patients with schizophrenia (p <0.05). Schizophrenic patients with anemia had a 7.68-fold greater risk (95% CI: 2.70 – 21.8) of aggression. Men with schizophrenia was associated with a 2.37-fold greater risk (95% CI: 1.00 – 5.60) of aggression. Conclusion: Anemia and men seems to be risk factors of aggression in patients with schizophrenia. Further multicenter studies with larger sample size is needed to support this finding.
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spelling doaj-art-c8406ca85ad145d7a9900e00ce0909822025-08-20T02:47:40ZengUniversitas PadjadjaranInternational Journal of Integrated Health Sciences2302-13812338-45062025-04-01131515510.15850/ijihs.v13n1.40291842Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric HospitalElly Noerhidajati0Yulia Ratna Sofa1Sri Woroasih2Intan Tri Hardini3University Islamic Sultan Agung, SemarangSultan Agung Islamic UniversityUniversity Islamic Sultan Agung, SemarangUniversity Islamic Sultan Agung, SemarangBackground: Anemia has been identified as a potential modifiable factor influencing aggression levels in individuals with schizophrenia. Objective: To investigate the association between anemia and incidence of aggression in patients with schizophrenia in Amino Gondohutomo Psychiatric Hospital, Semarang, Indonesia. Methods: A cross-sectional study was conducted between January 2022 and December 2023 on patients with schizophrenia in Amino Gondohutomo Psychiatric Hospital, Semarang, Indonesia. Subjects were selected using consecutive sampling technique, and individuals with affective mood disorder and lost to follow-up were excluded from the study. Data were obtained through patients’ medical records, PANSS-EC scores, and hemoglobin measuring devices. Chi-square test and logistic regression were applied for statistical analyses. Results: Of 100 participants, patients with schizophrenia presented with aggression were predominantly above 40 years old (26 patients, 81.3%), women (17 patients, 51.1%), and non-anemic (17 patients, 57.1%). Gender and anemia were significantly associated with aggression in patients with schizophrenia (p <0.05). Schizophrenic patients with anemia had a 7.68-fold greater risk (95% CI: 2.70 – 21.8) of aggression. Men with schizophrenia was associated with a 2.37-fold greater risk (95% CI: 1.00 – 5.60) of aggression. Conclusion: Anemia and men seems to be risk factors of aggression in patients with schizophrenia. Further multicenter studies with larger sample size is needed to support this finding.https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/4029aggressionanemiaschizophrenia
spellingShingle Elly Noerhidajati
Yulia Ratna Sofa
Sri Woroasih
Intan Tri Hardini
Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
International Journal of Integrated Health Sciences
aggression
anemia
schizophrenia
title Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
title_full Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
title_fullStr Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
title_full_unstemmed Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
title_short Anemia and Aggression Among Patients with Schizophrenia in Amino Gondohutomo Psychiatric Hospital
title_sort anemia and aggression among patients with schizophrenia in amino gondohutomo psychiatric hospital
topic aggression
anemia
schizophrenia
url https://journal.fk.unpad.ac.id/index.php/ijihs/article/view/4029
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