Exercise-mobilized donor lymphocyte infusions enhanced with cytokine stimulation for the prevention and treatment of leukemic relapse after allogeneic hematopoietic cell transplantation

Exercise-mobilized donor lymphocyte infusions enhanced with cytokine stimulation for the prevention and treatment of leukemic relapse after allogeneic hematopoietic cell transplantation

Donor lymphocyte infusions (DLI) are a standard therapy following allogeneic hematopoietic cell transplantation (alloHCT) for preventing and treating leukemic relapse in high-risk patients, particularly those with myeloid malignancies such as acute myeloid leukemia (AML), chronic myeloid leukemia (C...

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Bibliographic Details
Main Authors: London M. McDougal, Forrest L. Baker, Michael P. Gustafson, Emmanuel Katsanis, Richard J. Simpson
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
hematological cancer
cell therapy
exercise immunology
exercise oncology
adrenergic receptors
cardiorespiratory fitness
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1563972/full
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