Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice.

<h4>Background</h4>Data available on the immunomodulatory properties of neural stem/precursor cells (NPC) support their possible use as modulators for immune-mediated process. The aim of this study was to define whether NPC administered in combination with pancreatic islets prevents reje...

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Main Authors: Raffaella Melzi, Barbara Antonioli, Alessia Mercalli, Manuela Battaglia, Andrea Valle, Stefano Pluchino, Rossella Galli, Valeria Sordi, Emanuele Bosi, Gianvito Martino, Ezio Bonifacio, Claudio Doglioni, Lorenzo Piemonti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010357&type=printable
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