Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)

The vacuolar proton pump ATPase (V-H+-ATPase), which is a multi-subunit membrane protein complex, plays a major role in the activation of ion and nutrient transport and has been suggested to be involved in several physiological processes, such as cell expansion and salt tolerance. In this study, thr...

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Main Authors: Fa-wei WANG, Chao WANG, Yao SUN, Nan WANG, Xiao-wei LI, Yuan-yuan DONG, Na YAO, Xiu-ming LIU, Huan CHEN, Xi-feng CHEN, Zhen-min WANG, Hai-yan LI
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2016-10-01
Series:Journal of Integrative Agriculture
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095311916613990
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author Fa-wei WANG
Chao WANG
Yao SUN
Nan WANG
Xiao-wei LI
Yuan-yuan DONG
Na YAO
Xiu-ming LIU
Huan CHEN
Xi-feng CHEN
Zhen-min WANG
Hai-yan LI
author_facet Fa-wei WANG
Chao WANG
Yao SUN
Nan WANG
Xiao-wei LI
Yuan-yuan DONG
Na YAO
Xiu-ming LIU
Huan CHEN
Xi-feng CHEN
Zhen-min WANG
Hai-yan LI
author_sort Fa-wei WANG
collection DOAJ
description The vacuolar proton pump ATPase (V-H+-ATPase), which is a multi-subunit membrane protein complex, plays a major role in the activation of ion and nutrient transport and has been suggested to be involved in several physiological processes, such as cell expansion and salt tolerance. In this study, three genes encoding V-H+-ATPase subunits B (ScVHA-B, GenBank: JF826506), C (ScVHA-C, GenBank: JF826507) and H (ScVHA-H, GenBank: JF826508) were isolated from the halophyte Suaeda corniculata. The transcript levels of ScVHA-B, ScVHA-C and ScVHA-H were increased by salt, drought and saline-alkali treatments. V-H+-ATPase activity was also examined under salt, drought and saline-alkali stresses. The results showed that V-H+-ATPase activity was correlated with salt, drought and saline-alkali stress. Furthermore, V-H+-ATPase subunits B, C and H (ScVHA-B, ScVHA-C and ScVHA-H) from S. corniculata were introduced separately into the alfalfa genome. The transgenic alfalfa was verified by Southern and Northern blot analysis. During salt and saline-alkali stresses, transgenic lines carrying the B, C and H subunits had higher germination rates than the wild type (WT). More free proline, higher superoxide dismutase (SOD) activity and lower malondialdehyde (MDA) levels were detected in the transgenic plants under salt and saline-alkali treatments. Moreover, the ScVHA-B transgenic lines showed greater tolerance to salt and saline-alkali stresses than the WT. These results suggest that overexpression of ScVHA-B, ScVHA-C and ScVHA-H improves tolerance to salt and saline-alkali stresses in transgenic alfalfa.
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series Journal of Integrative Agriculture
spelling doaj-art-c824346665134405b93f28682c3eccc92025-08-20T03:57:47ZengKeAi Communications Co., Ltd.Journal of Integrative Agriculture2095-31192016-10-0115102279228910.1016/S2095-3119(16)61399-0Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)Fa-wei WANG0Chao WANG1Yao SUN2Nan WANG3Xiao-wei LI4Yuan-yuan DONG5Na YAO6Xiu-ming LIU7Huan CHEN8Xi-feng CHEN9Zhen-min WANG10Hai-yan LI11College of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. China; WANG Fa-wei, Mobile: +86-13596076186College of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. ChinaJilin Technology Innovation Center for Soybean Region, Jilin Agricultural University, Changchun 130118, P.R. ChinaJilin Technology Innovation Center for Soybean Region, Jilin Agricultural University, Changchun 130118, P.R. ChinaCollege of Life Sciences, Jilin Agricultural University/Engineering Research Center of Bioreactor and Pharmaceutical Development, Ministry of Education, Changchun 130118, P.R. China; Correspondence LI Hai-yan, Tel: +86-431-84532885, Fax: +86-431-84533427The vacuolar proton pump ATPase (V-H+-ATPase), which is a multi-subunit membrane protein complex, plays a major role in the activation of ion and nutrient transport and has been suggested to be involved in several physiological processes, such as cell expansion and salt tolerance. In this study, three genes encoding V-H+-ATPase subunits B (ScVHA-B, GenBank: JF826506), C (ScVHA-C, GenBank: JF826507) and H (ScVHA-H, GenBank: JF826508) were isolated from the halophyte Suaeda corniculata. The transcript levels of ScVHA-B, ScVHA-C and ScVHA-H were increased by salt, drought and saline-alkali treatments. V-H+-ATPase activity was also examined under salt, drought and saline-alkali stresses. The results showed that V-H+-ATPase activity was correlated with salt, drought and saline-alkali stress. Furthermore, V-H+-ATPase subunits B, C and H (ScVHA-B, ScVHA-C and ScVHA-H) from S. corniculata were introduced separately into the alfalfa genome. The transgenic alfalfa was verified by Southern and Northern blot analysis. During salt and saline-alkali stresses, transgenic lines carrying the B, C and H subunits had higher germination rates than the wild type (WT). More free proline, higher superoxide dismutase (SOD) activity and lower malondialdehyde (MDA) levels were detected in the transgenic plants under salt and saline-alkali treatments. Moreover, the ScVHA-B transgenic lines showed greater tolerance to salt and saline-alkali stresses than the WT. These results suggest that overexpression of ScVHA-B, ScVHA-C and ScVHA-H improves tolerance to salt and saline-alkali stresses in transgenic alfalfa.http://www.sciencedirect.com/science/article/pii/S2095311916613990vacuolar proton pumpsalt tolerancesaline-alkali tolerancealfalfa
spellingShingle Fa-wei WANG
Chao WANG
Yao SUN
Nan WANG
Xiao-wei LI
Yuan-yuan DONG
Na YAO
Xiu-ming LIU
Huan CHEN
Xi-feng CHEN
Zhen-min WANG
Hai-yan LI
Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
Journal of Integrative Agriculture
vacuolar proton pump
salt tolerance
saline-alkali tolerance
alfalfa
title Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
title_full Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
title_fullStr Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
title_full_unstemmed Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
title_short Overexpression of vacuolar proton pump ATPase (V-H+-ATPase) subunits B, C and H confers tolerance to salt and saline-alkali stresses in transgenic alfalfa (Medicago sativa L.)
title_sort overexpression of vacuolar proton pump atpase v h atpase subunits b c and h confers tolerance to salt and saline alkali stresses in transgenic alfalfa medicago sativa l
topic vacuolar proton pump
salt tolerance
saline-alkali tolerance
alfalfa
url http://www.sciencedirect.com/science/article/pii/S2095311916613990
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