Green and white analytical approach for parallel quantification of gabapentin and methylcobalamin in medicinal products using inventive RP-HPLC technique

Green and white analytical approach for parallel quantification of gabapentin and methylcobalamin in medicinal products using inventive RP-HPLC technique

Abstract A simple, selective, and environmentally sustainable RP-HPLC method was developed for simultaneous quantification of gabapentin (GAB) and Methylcobalamin (MET) in pharmaceutical products. Separation was achieved on a Zorbax Eclipse C8 column (150 × 4.6 mm, 3.5 μm) using a green mobile phase...

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Bibliographic Details
Main Authors: Samar M. Mahgoub, Fahad M. Alminderej, Ammena Y. Binsaleh, Bandar R. Alsehli, Sayed M. Saleh, Mahmoud A. Mohamed
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Gabapentin
Methylcobalamin
Green and white approach
RP- HPLC
Stability
Online Access:https://doi.org/10.1038/s41598-025-07056-9
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