Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival

Malignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old f...

Full description

Saved in:
Bibliographic Details
Main Authors: Yara A. Alnashwan, Khaled A. H. Ali, Samir S. Amr
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2019/9576487
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850172447786008576
author Yara A. Alnashwan
Khaled A. H. Ali
Samir S. Amr
author_facet Yara A. Alnashwan
Khaled A. H. Ali
Samir S. Amr
author_sort Yara A. Alnashwan
collection DOAJ
description Malignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old female who had MGCT arising in the anterior abdominal wall and developed massive metastatic deposits in both lungs and in the right inguinal lymph nodes, with prolonged survival for 11 years. A brief review of the literature is presented.
format Article
id doaj-art-c81e1ca3d53a480999eae99cd2f0c60e
institution OA Journals
issn 2090-6781
2090-679X
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Pathology
spelling doaj-art-c81e1ca3d53a480999eae99cd2f0c60e2025-08-20T02:20:06ZengWileyCase Reports in Pathology2090-67812090-679X2019-01-01201910.1155/2019/95764879576487Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged SurvivalYara A. Alnashwan0Khaled A. H. Ali1Samir S. Amr2Department of Pathology, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaDepartment of Pathology, Almana General Hospital, Dammam, Saudi ArabiaDepartment of Pathology and Laboratory Medicine, King Fahad Specialist Hospital, Dammam, Saudi ArabiaMalignant granular cell tumor (MGCT) is a rare high-grade mesenchymal tumor of Schwann cell origin. MGCTs commonly affect thigh, extremity, and trunk; however, involvement of the abdominal wall is quite rare. It has poor prognosis with 39% mortality rate in 3-year interval. We report a 50-year-old female who had MGCT arising in the anterior abdominal wall and developed massive metastatic deposits in both lungs and in the right inguinal lymph nodes, with prolonged survival for 11 years. A brief review of the literature is presented.http://dx.doi.org/10.1155/2019/9576487
spellingShingle Yara A. Alnashwan
Khaled A. H. Ali
Samir S. Amr
Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
Case Reports in Pathology
title Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
title_full Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
title_fullStr Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
title_full_unstemmed Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
title_short Metastasizing Malignant Granular Cell Tumor (Abrikossoff Tumor) of the Anterior Abdominal Wall, with Prolonged Survival
title_sort metastasizing malignant granular cell tumor abrikossoff tumor of the anterior abdominal wall with prolonged survival
url http://dx.doi.org/10.1155/2019/9576487
work_keys_str_mv AT yaraaalnashwan metastasizingmalignantgranularcelltumorabrikossofftumoroftheanteriorabdominalwallwithprolongedsurvival
AT khaledahali metastasizingmalignantgranularcelltumorabrikossofftumoroftheanteriorabdominalwallwithprolongedsurvival
AT samirsamr metastasizingmalignantgranularcelltumorabrikossofftumoroftheanteriorabdominalwallwithprolongedsurvival