In vitro toxicological evaluation of pouched portioned oral nicotine products

In vitro toxicological evaluation of pouched portioned oral nicotine products

IntroductionModern oral nicotine pouch products (ONPs) are a category of oral nicotine products which contain pharmaceutical-grade nicotine, flavors, and other food-grade ingredients but no tobacco leaf. Recent reports indicate that ONPs in general do not contain (or only at minimal levels) the harm...

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Bibliographic Details
Main Authors: Brian M. Keyser, Robert Leverette, Reagan McRae, John Wertman, Tom Shutsky, Ken Szeliga, Patrudu Makena, Kristen G. Jordan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Toxicology
Subjects:
modern oral nicotine pouches
in vitro toxicity assays
mutagenicity
genotoxicity
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2024.1452274/full
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