Intravitreal Melphalan Chemotherapy for Vitreous Seeds in Retinoblastoma

Intravitreal Melphalan Chemotherapy for Vitreous Seeds in Retinoblastoma

Objective. To evaluate our experience with intravitreal melphalan chemotherapy as a second-line regimen for RB patients with refractory or recurrent vitreous seeds. Methods. A retrospective case series of 16 eyes from 16 patients with intraocular RB who received intravitreal melphalan chemotherapy u...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yacoub A. Yousef, Amal M. Noureldin, Iyad Sultan, Rasha Deebajah, Maysa Al-Hussaini, Munir Shawagfeh, Mustafa Mehyar, Mona Mohammad, Imad Jaradat, Ibrahim AlNawaiseh
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Journal of Ophthalmology
Online Access:	http://dx.doi.org/10.1155/2020/8628525
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Intravitreal and Subconjunctival Melphalan for Retinoblastoma in Transgenic Mice
by: Nisha V. Shah, et al.
Published: (2014-01-01)

Familial Retinoblastoma: Raised Awareness Improves Early Diagnosis and Outcome
by: Ibrahim Al-Nawaiseh, et al.
Published: (2017-01-01)

Intravitreal Bevacizumab in Vitreous Hemorrhage and Diabetes Mellitus
by: Beuy Joob, et al.
Published: (2017-03-01)

Vitreous Inflammation Associated with Intravitreal Anti-VEGF Pharmacotherapy
by: Shivi Agrawal, et al.
Published: (2013-01-01)

Retinal changes after intravitreal injections of various concentrations of antiproliferative medication Melphalan: an experimental and morphological study
by: I. P. Khoroshilova-Maslova, et al.
Published: (2018-10-01)

Optical Coherence Tomography Based Differentiation of Intravitreal Particles in Posterior Uveitis and Vitreous Hemorrhage
by: Ya. A. Kalinicheva, et al.
Published: (2023-10-01)

Intravitreal Ranibizumab Injection as an Adjuvant in the Treatment of Neovascular Glaucoma Accompanied by Vitreous Hemorrhage after Diabetic Vitrectomy
by: Xi Shen, et al.
Published: (2016-01-01)

Retinocytoma: understanding pathogenesis, diagnosis, and treatment approaches
by: Maysa Al-Hussaini, et al.
Published: (2025-02-01)

Effect of Estimated Individual Vitreous Volume on Intraocular Pressure Spikes after Intravitreal Anti-Vascular Endothelial Growth Factors Injection
by: Nurullah Koçak, et al.
Published: (2025-01-01)

Cost-effectiveness analysis of daratumumab plus bortezomib, melphalan and prednisone versus bortezomib, melphalan and prednisone in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation
by: Dan Xie, et al.
Published: (2025-02-01)

Diffuse Infiltrating Retinoblastoma - Atypical Presentation of Retinoblastoma in late childhood
by: Manu Saini, et al.
Published: (2016-04-01)

Lens subluxation in retinoblastoma – Where does it fit in the classification of retinoblastoma
by: Vikas Khetan, et al.
Published: (2024-12-01)

Quantum Chemical Studies of Bendamustine and Melphalan in Water as Antiblood Cancer Agents
by: Roman Boča, et al.
Published: (2024-12-01)

Vitreous Substitutes
by: Shorya Vardhan Azad, et al.
Published: (2012-07-01)

Mathematical Modeling of Eyeball Vitreous Cavity and Software Based Thereon for Automatic Calculation of Individual Doses of Antibiotics for Intravitreal Injection in Treating Bacterial Endophthalmitis
by: V. N. Kazaykin, et al.
Published: (2020-04-01)

Vitreous Hemorrhage in Pediatric Age Group
by: Dora H. AlHarkan, et al.
Published: (2014-01-01)

Bortezomib (velcade) plus melphalan and prednisone in elderly untreated patients with multiple myeloma
by: S. S. Bessmeltsev, et al.
Published: (2022-11-01)

Repeated use of hybrid isolated chemoperfusion with melphalan in non-resectable liver malignancy
by: A. I. Babich, et al.
Published: (2024-03-01)

A pilot study of intraoperative melphalan to prevent recurrent PVR: the IOMPVR study
by: Carlos A. Moreira-Neto, et al.
Published: (2025-05-01)

Melphalan delivery and co-delivery nanoformulations for cancer therapy: A comprehensive review
by: Hamidreza Abdouss, et al.
Published: (2024-12-01)

Update on Retinoblastoma Therapies
by: Cristina A. Martínez Arce, et al.
Published: (2025-07-01)

Recent Developments in Retinoblastoma
by: Raksha Rao, et al.
Published: (2016-07-01)

Isolated chemohyperthermal perfusion of the liver with melphalan in the treatment of unresectable liver metastases with uveal melanoma
by: A. D. Kaprin, et al.
Published: (2021-12-01)

Crystal Structure of Melphalan Hydrochloride and Its Association with Caffeine Improves Its Antineoplastic Action
by: Juliana Pereira da Silva, et al.
Published: (2025-05-01)

NAD+ metabolism restriction boosts high-dose melphalan efficacy in patients with multiple myeloma
by: Debora Soncini, et al.
Published: (2025-03-01)

Capacity to Treat Retinoblastoma in the Philippines
by: Sandra Joan Worak-Tan MD, et al.
Published: (2023-12-01)

Plaque radiotherapy in the management of retinoblastoma
by: H Kiratli, et al.
Published: (1998-07-01)

Refractive Errors in Children with Retinoblastoma
by: S. V. Saakyan, et al.
Published: (2020-04-01)

The Broiling Soup of Retinoblastoma Genetics
by: Kaur Amritjeet, et al.
Published: (2020-07-01)

Epigenetic Reprogramming by Decitabine in Retinoblastoma
by: Lisa Gherardini, et al.
Published: (2025-04-01)

Retinoblastoma with and without Extraocular Tumor Extension
by: Swathi Kaliki, MD, et al.
Published: (2025-03-01)

Vital Stains in Retina and Vitreous
by: Shreyangshi Dipta, et al.
Published: (2022-01-01)

Indisulam synergizes with melphalan to inhibit Multiple Myeloma malignancy via targeting TOP2A.
by: Chengyu Wu, et al.
Published: (2024-01-01)

Clinical Features of Children with Retinoblastoma and Neuroblastoma
by: Xiaolian Fang, et al.
Published: (2020-01-01)

Retinoblastoma: Evolving Concepts and Future Challenges
by: Mateusz Wiekiera, et al.
Published: (2025-08-01)

Retinoblastoma Morphology after Local Chemotherapy
by: S. V. Saakyan, et al.
Published: (2021-10-01)

A Comparison of Retinoblastoma Cases in the Philippines
by: Roland Joseph D. Tan, MD, MS, MIH, et al.
Published: (2024-12-01)

Postherpetic pruritus in a child with retinoblastoma
by: Sinem Akgül, et al.
Published: (2009-02-01)

Orbital Myiasis: An Unusual Presentation of Retinoblastoma
by: Minhaz M. Karkhanawala, et al.
Published: (2018-10-01)

Update on Intra-Arterial Chemotherapy for Retinoblastoma
by: Mario Zanaty, et al.
Published: (2014-01-01)