Bridging the marrow: a co-culture-platform of leukemia cells and MS5-derived stromal cells or adipocytes
Abstract In the context of acute lymphoblastic leukemia (ALL), the bone marrow microenvironment (BMM) plays a crucial role in providing pro-survival signals, as evident from the rapid spontaneous cell death observed in ex-vivo cultures of primary ALL cells. Among the diverse cell types within the BM...
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| Main Authors: | Julia Zinngrebe, Elena Dorothea Brenner, Ferdinand Schlichtig, Ulrich Stifel, Daniel Tews, Jana Falk, Dominik Schlotter, Rahel Fitzel, Lüder-Hinrich Meyer, Klaus-Michael Debatin, Pamela Fischer-Posovszky |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-025-02631-5 |
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