How leaky is the gut in Parkinson’s disease?

How leaky is the gut in Parkinson’s disease?

Summary: The intestinal epithelial barrier (IEB) plays a critical role in health and disease by regulating the absorption of nutrients, electrolytes and water while preventing gut translocation of pathogens. A compromised intestinal barrier has been reported in Parkinson’s disease (PD) further reinf...

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Main Authors:	Pascal Derkinderen, François Cossais, Kristína Kulcsárová, Matej Škorvánek, Loïc Sellier-Montaigne, Emmanuel Coron, Laurène Leclair-Visonneau, Silvia Cerri, Carolina Pellegrini, Malvyne Rolli-Derkinderen
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Series:	EBioMedicine
Subjects:	Parkinson’s disease Intestinal epithelial barrier Intestinal permeability Tight junctions Ussing chamber Organoids
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396425002403
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