Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research
Molecular imaging, including fluorescence imaging (FMI), bioluminescence imaging (BLI), positron emission tomography (PET), single-photon emission-computed tomography (SPECT), and computed tomography (CT), has a pivotal role...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | International Journal of Biomedical Imaging |
| Online Access: | http://dx.doi.org/10.1155/2011/370701 |
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| _version_ | 1832550726516080640 |
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| author | Xibo Ma Jie Tian Xin Yang Chenghu Qin |
| author_facet | Xibo Ma Jie Tian Xin Yang Chenghu Qin |
| author_sort | Xibo Ma |
| collection | DOAJ |
| description | Molecular imaging,
including fluorescence imaging (FMI),
bioluminescence imaging (BLI), positron emission
tomography (PET), single-photon emission-computed tomography (SPECT), and computed tomography
(CT), has a pivotal role in the
process of tumor and relevant drug research. CT,
especially Micro-CT, can provide the anatomic
information for a region of interest (ROI); PET
and SPECT can provide functional information for
the ROI. BLI and FMI can provide optical
information for an ROI. Tumor angiogenesis and
relevant drug development is a lengthy,
high-risk, and costly process, in which a novel
drug needs about 10–15 years of testing to
obtain Federal Drug Association (FDA) approval.
Molecular imaging can enhance the development
process by understanding the tumor mechanisms
and drug activity. In this paper, we focus on
tumor angiogenesis, and we review the
characteristics of molecular imaging modalities
and their applications in tumor angiogenesis and
relevant drug research. |
| format | Article |
| id | doaj-art-c80cf79ce05547baa99b198617b41665 |
| institution | Kabale University |
| issn | 1687-4188 1687-4196 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomedical Imaging |
| spelling | doaj-art-c80cf79ce05547baa99b198617b416652025-02-03T06:06:02ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962011-01-01201110.1155/2011/370701370701Molecular Imaging in Tumor Angiogenesis and Relevant Drug ResearchXibo Ma0Jie Tian1Xin Yang2Chenghu Qin3Intelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, ChinaIntelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, ChinaIntelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, ChinaIntelligent Medical Research Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, ChinaMolecular imaging, including fluorescence imaging (FMI), bioluminescence imaging (BLI), positron emission tomography (PET), single-photon emission-computed tomography (SPECT), and computed tomography (CT), has a pivotal role in the process of tumor and relevant drug research. CT, especially Micro-CT, can provide the anatomic information for a region of interest (ROI); PET and SPECT can provide functional information for the ROI. BLI and FMI can provide optical information for an ROI. Tumor angiogenesis and relevant drug development is a lengthy, high-risk, and costly process, in which a novel drug needs about 10–15 years of testing to obtain Federal Drug Association (FDA) approval. Molecular imaging can enhance the development process by understanding the tumor mechanisms and drug activity. In this paper, we focus on tumor angiogenesis, and we review the characteristics of molecular imaging modalities and their applications in tumor angiogenesis and relevant drug research.http://dx.doi.org/10.1155/2011/370701 |
| spellingShingle | Xibo Ma Jie Tian Xin Yang Chenghu Qin Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research International Journal of Biomedical Imaging |
| title | Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research |
| title_full | Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research |
| title_fullStr | Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research |
| title_full_unstemmed | Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research |
| title_short | Molecular Imaging in Tumor Angiogenesis and Relevant Drug Research |
| title_sort | molecular imaging in tumor angiogenesis and relevant drug research |
| url | http://dx.doi.org/10.1155/2011/370701 |
| work_keys_str_mv | AT xiboma molecularimagingintumorangiogenesisandrelevantdrugresearch AT jietian molecularimagingintumorangiogenesisandrelevantdrugresearch AT xinyang molecularimagingintumorangiogenesisandrelevantdrugresearch AT chenghuqin molecularimagingintumorangiogenesisandrelevantdrugresearch |