Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease
Ambulatory arterial stiffness index (AASI) is a parameter obtained from ambulatory blood pressure monitoring (ABPM) that correlates with clinical endpoints. The aim of this study was to compare AASI in nondiabetic hypertensive patients with and without chronic kidney disease (CKD). Subjects with sys...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2012/178078 |
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| author | Ronaldo Altenburg Gismondi Mario Fritsch Neves Wille Oigman Rachel Bregman |
| author_facet | Ronaldo Altenburg Gismondi Mario Fritsch Neves Wille Oigman Rachel Bregman |
| author_sort | Ronaldo Altenburg Gismondi |
| collection | DOAJ |
| description | Ambulatory arterial stiffness index (AASI) is a parameter obtained from ambulatory blood pressure monitoring (ABPM) that correlates with clinical endpoints. The aim of this study was to compare AASI in nondiabetic hypertensive patients with and without chronic kidney disease (CKD). Subjects with systemic arterial hypertension (SAH, n=30) with normal renal function, aged 40 to 75 years, were compared to hypertensive patients with CKD (n=30) presenting estimated glomerular filtration rate (eGFR) <60 mL/min by MDRD formula. ABPM was carried out in all patients. In CKD group, eGFR was 35.3 ± 2.8 ml/min. The mean 24-hour systolic and diastolic blood pressure (BP) was similar in both groups. AASI was significantly higher in CKD group (0.45±0.03 versus 0.37±0.02, P<0.05), positively correlated to age (r=0.38, P<0.01) and pulse pressure (r=0.43, P<0.01) and negatively correlated to nocturnal BP fall (r=-0.28, P=0.03). These findings indicate the presence of stiffer vessels in CKD hypertensive patients. |
| format | Article |
| id | doaj-art-c80afc8903054a47a0e04a054c48bf85 |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-c80afc8903054a47a0e04a054c48bf852025-02-03T01:00:26ZengWileyInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/178078178078Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney DiseaseRonaldo Altenburg Gismondi0Mario Fritsch Neves1Wille Oigman2Rachel Bregman3Department of Clinical Medicine, Rio de Janeiro State University, Rio de Janeiro, RJ, BrazilDepartment of Clinical Medicine, Rio de Janeiro State University, Rio de Janeiro, RJ, BrazilDepartment of Clinical Medicine, Rio de Janeiro State University, Rio de Janeiro, RJ, BrazilNephrology Division, Rio de Janeiro State University, Rio de Janeiro, RJ, BrazilAmbulatory arterial stiffness index (AASI) is a parameter obtained from ambulatory blood pressure monitoring (ABPM) that correlates with clinical endpoints. The aim of this study was to compare AASI in nondiabetic hypertensive patients with and without chronic kidney disease (CKD). Subjects with systemic arterial hypertension (SAH, n=30) with normal renal function, aged 40 to 75 years, were compared to hypertensive patients with CKD (n=30) presenting estimated glomerular filtration rate (eGFR) <60 mL/min by MDRD formula. ABPM was carried out in all patients. In CKD group, eGFR was 35.3 ± 2.8 ml/min. The mean 24-hour systolic and diastolic blood pressure (BP) was similar in both groups. AASI was significantly higher in CKD group (0.45±0.03 versus 0.37±0.02, P<0.05), positively correlated to age (r=0.38, P<0.01) and pulse pressure (r=0.43, P<0.01) and negatively correlated to nocturnal BP fall (r=-0.28, P=0.03). These findings indicate the presence of stiffer vessels in CKD hypertensive patients.http://dx.doi.org/10.1155/2012/178078 |
| spellingShingle | Ronaldo Altenburg Gismondi Mario Fritsch Neves Wille Oigman Rachel Bregman Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease International Journal of Hypertension |
| title | Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease |
| title_full | Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease |
| title_fullStr | Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease |
| title_full_unstemmed | Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease |
| title_short | Ambulatory Arterial Stiffness Index Is Higher in Hypertensive Patients with Chronic Kidney Disease |
| title_sort | ambulatory arterial stiffness index is higher in hypertensive patients with chronic kidney disease |
| url | http://dx.doi.org/10.1155/2012/178078 |
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