Application of a macrocyclization strategy in kinase inhibitor development
Kinases have a pivotal role in phosphorylation and kinase dysregulation has been implicated in the occurrence and progression of various diseases. By mid-2024 the Food and Drug Administration had approved 81 small-molecule kinase inhibitors targeting greater than 30 kinases, providing substantial cl...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Compuscript Ltd
2025-01-01
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| Series: | Acta Materia Medica |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0070 |
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