Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis
Abstract Background Suicide remains a major risk factor for individuals suffering from schizophrenia and its prodromal state (i.e., Ultra-High Risk for Psychosis). However, less is known about the prevalence of suicidal behaviour among the adolescent and youth UHR population, a demographic vulnerabl...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2025-01-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933825024447/type/journal_article |
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| author | Shi Han Ang Siddarth Venkateswaran Mahir Bakulkumar Goda Kuhanesan N. C. Naidu Ganesh Kudva Kundadak Mythily Subramaniam |
| author_facet | Shi Han Ang Siddarth Venkateswaran Mahir Bakulkumar Goda Kuhanesan N. C. Naidu Ganesh Kudva Kundadak Mythily Subramaniam |
| author_sort | Shi Han Ang |
| collection | DOAJ |
| description | Abstract
Background
Suicide remains a major risk factor for individuals suffering from schizophrenia and its prodromal state (i.e., Ultra-High Risk for Psychosis). However, less is known about the prevalence of suicidal behaviour among the adolescent and youth UHR population, a demographic vulnerable to the psychosocial and environmental risk factors of suicide. This review aims to synthesise existing literature on the prevalence of suicidal ideation and behaviour in the adolescent and youth at Ultra-High Risk for Psychosis (UHR), and the associations between suicidal behaviour and its correlates.
Methods
The databases PsycINFO, PubMed, Embase, Cochrane Library, Web of Science, and Scopus were accessed up to July 2024. A meta-analysis of prevalence was subsequently performed for lifetime suicidal ideation, lifetime non-suicidal self-injury, lifetime suicidal attempt, and current suicidal ideation. A narrative review was also carried out for the correlates of suicidal behaviour amongst adolescents and youth in the UHR population.
Results
Studies were included in this meta-analysis. Meta-analysis revealed a high prevalence of lifetime suicidal ideation (58%), lifetime non-suicidal self-injury (37%), lifetime suicidal attempt (25%), and current (2 week) suicidal ideation (56%). The narrative review revealed that a personal transition to psychosis and a positive family history of psychosis were associated with suicidal attempts, while depression was associated with both suicidal attempts and suicidal ideation.
Conclusion
The prevalence of suicidal ideation and behaviour among UHR adolescents and youth is high and comparable to that of the general UHR population. Existing measures that mitigate suicide risk in the general UHR population should be adopted for the youth context.
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| format | Article |
| id | doaj-art-c7ffbcb0c8d545e38c3cec6690ae86d1 |
| institution | DOAJ |
| issn | 0924-9338 1778-3585 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj-art-c7ffbcb0c8d545e38c3cec6690ae86d12025-08-20T03:11:09ZengCambridge University PressEuropean Psychiatry0924-93381778-35852025-01-016810.1192/j.eurpsy.2025.2444Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysisShi Han Ang0https://orcid.org/0009-0006-8052-549XSiddarth Venkateswaran1Mahir Bakulkumar Goda2https://orcid.org/0009-0009-9824-732XKuhanesan N. C. Naidu3https://orcid.org/0009-0007-4118-9195Ganesh Kudva Kundadak4https://orcid.org/0000-0001-9157-2175Mythily Subramaniam5https://orcid.org/0000-0003-4530-1096Yong Loo Lin School of Medicine, National University of Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, SingaporeYong Loo Lin School of Medicine, National University of Singapore, SingaporeDepartment of Psychological Medicine, National University Hospital, Singapore Saw Swee Hock School of Public Health, National University of Singapore, SingaporeDepartment of Psychological Medicine, National University Hospital, Singapore Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, SingaporeDepartment of Psychological Medicine, National University Hospital, Singapore Research Division, Institute of Mental Health, Singapore Lee Kong Chian School of Medicine, Nanyang Technological University, SingaporeAbstract Background Suicide remains a major risk factor for individuals suffering from schizophrenia and its prodromal state (i.e., Ultra-High Risk for Psychosis). However, less is known about the prevalence of suicidal behaviour among the adolescent and youth UHR population, a demographic vulnerable to the psychosocial and environmental risk factors of suicide. This review aims to synthesise existing literature on the prevalence of suicidal ideation and behaviour in the adolescent and youth at Ultra-High Risk for Psychosis (UHR), and the associations between suicidal behaviour and its correlates. Methods The databases PsycINFO, PubMed, Embase, Cochrane Library, Web of Science, and Scopus were accessed up to July 2024. A meta-analysis of prevalence was subsequently performed for lifetime suicidal ideation, lifetime non-suicidal self-injury, lifetime suicidal attempt, and current suicidal ideation. A narrative review was also carried out for the correlates of suicidal behaviour amongst adolescents and youth in the UHR population. Results Studies were included in this meta-analysis. Meta-analysis revealed a high prevalence of lifetime suicidal ideation (58%), lifetime non-suicidal self-injury (37%), lifetime suicidal attempt (25%), and current (2 week) suicidal ideation (56%). The narrative review revealed that a personal transition to psychosis and a positive family history of psychosis were associated with suicidal attempts, while depression was associated with both suicidal attempts and suicidal ideation. Conclusion The prevalence of suicidal ideation and behaviour among UHR adolescents and youth is high and comparable to that of the general UHR population. Existing measures that mitigate suicide risk in the general UHR population should be adopted for the youth context. https://www.cambridge.org/core/product/identifier/S0924933825024447/type/journal_articleultra high riskfirst episode psychosisschizophreniasuicidechild and adolescent psychiatry |
| spellingShingle | Shi Han Ang Siddarth Venkateswaran Mahir Bakulkumar Goda Kuhanesan N. C. Naidu Ganesh Kudva Kundadak Mythily Subramaniam Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis European Psychiatry ultra high risk first episode psychosis schizophrenia suicide child and adolescent psychiatry |
| title | Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis |
| title_full | Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis |
| title_fullStr | Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis |
| title_full_unstemmed | Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis |
| title_short | Prevalence of suicidal behaviour in adolescents and youth at ultra-high risk for psychosis: A systematic review and meta-analysis |
| title_sort | prevalence of suicidal behaviour in adolescents and youth at ultra high risk for psychosis a systematic review and meta analysis |
| topic | ultra high risk first episode psychosis schizophrenia suicide child and adolescent psychiatry |
| url | https://www.cambridge.org/core/product/identifier/S0924933825024447/type/journal_article |
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