Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer

Understanding drug resistance in cancer is of importance in treatment. Cancer stem cells are main factor for drug resistance. Therefore, the possible gene/gene interactions/proteins were explored in our study using a cancer stem cell-enriched population (H1299/S) derived from a parental non-small ce...

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Main Authors: Dere Egemen, Akgün Oğuzhan, Aztopal Nazlıhan, Ulukaya Engin
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2024-0181
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author Dere Egemen
Akgün Oğuzhan
Aztopal Nazlıhan
Ulukaya Engin
author_facet Dere Egemen
Akgün Oğuzhan
Aztopal Nazlıhan
Ulukaya Engin
author_sort Dere Egemen
collection DOAJ
description Understanding drug resistance in cancer is of importance in treatment. Cancer stem cells are main factor for drug resistance. Therefore, the possible gene/gene interactions/proteins were explored in our study using a cancer stem cell-enriched population (H1299/S) derived from a parental non-small cell lung cancer cell line (H1299/P).
format Article
id doaj-art-c7f6106bbacc4e3c8d689484ae5ac096
institution OA Journals
issn 1303-829X
language English
publishDate 2025-01-01
publisher De Gruyter
record_format Article
series Türk Biyokimya Dergisi
spelling doaj-art-c7f6106bbacc4e3c8d689484ae5ac0962025-08-20T01:48:38ZengDe GruyterTürk Biyokimya Dergisi1303-829X2025-01-0150219820410.1515/tjb-2024-0181Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancerDere Egemen0Akgün Oğuzhan1Aztopal Nazlıhan2Ulukaya Engin3Department of Biology, Art and Science Faculty, 37523Bursa Uludag University, Bursa, TürkiyeDepartment of Biology, Instütute of Science, Bursa Uludag University, Bursa, TürkiyeDepartment of Molecular Biology, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, TürkiyeDepartment of Clinical Biochemistry, Faculty of Medicine, Istinye University, Istanbul, TürkiyeUnderstanding drug resistance in cancer is of importance in treatment. Cancer stem cells are main factor for drug resistance. Therefore, the possible gene/gene interactions/proteins were explored in our study using a cancer stem cell-enriched population (H1299/S) derived from a parental non-small cell lung cancer cell line (H1299/P).https://doi.org/10.1515/tjb-2024-0181cisplatindrug resistancegenelung cancerstem cell
spellingShingle Dere Egemen
Akgün Oğuzhan
Aztopal Nazlıhan
Ulukaya Engin
Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
Türk Biyokimya Dergisi
cisplatin
drug resistance
gene
lung cancer
stem cell
title Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
title_full Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
title_fullStr Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
title_full_unstemmed Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
title_short Investigation into drug resistance to cisplatin in cancer stem cell-enriched population in non-small cell lung cancer
title_sort investigation into drug resistance to cisplatin in cancer stem cell enriched population in non small cell lung cancer
topic cisplatin
drug resistance
gene
lung cancer
stem cell
url https://doi.org/10.1515/tjb-2024-0181
work_keys_str_mv AT dereegemen investigationintodrugresistancetocisplatinincancerstemcellenrichedpopulationinnonsmallcelllungcancer
AT akgunoguzhan investigationintodrugresistancetocisplatinincancerstemcellenrichedpopulationinnonsmallcelllungcancer
AT aztopalnazlıhan investigationintodrugresistancetocisplatinincancerstemcellenrichedpopulationinnonsmallcelllungcancer
AT ulukayaengin investigationintodrugresistancetocisplatinincancerstemcellenrichedpopulationinnonsmallcelllungcancer