Redefining “normal”: discovery of aneuploid epithelial cells in healthy breast tissue

Redefining “normal”: discovery of aneuploid epithelial cells in healthy breast tissue

Saved in:

Bibliographic Details
Main Authors:	Xiaoyan Chen, Xiaoling Liu, Jiapeng Xue, Zhi Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Oncology
Subjects:	aneuploid epithelial cells breast tissue copy number alterations cancer breast cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1558977/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Decoding the pathological and genomic profile of epithelial ovarian cancer
by: Rim Rejaibi, et al.
Published: (2024-11-01)

Analysis of cytogenetics for the aneuploids in pentaploid progenies from intergeneric cross between Brassica napus and Orychophragmus violaceus
by: WU Jian-guo, et al.
Published: (2002-11-01)

Copy number alternations of the 17q23-rs6504950 locus are associated with advanced breast cancers in Taiwanese women
by: Chien-Yu Lin, et al.
Published: (2020-01-01)

In situ phenotypic and karyotypic co-detection of aneuploid TCs and TECs in cytological specimens with abnormal cervical screening results
by: Yanling Wang, et al.
Published: (2025-05-01)

Retrospective Analysis of Transcriptomic Differences between Triple-Negative Breast Cancer (TNBC) and non-TNBC
by: Çağlar Berkel
Published: (2024-05-01)

ASSOCIATION OF THE COMBINATION OF STEMNESS GENE AMPLIFICATIONS AND COPY NUMBER ABERRATIONS OF WNT-SIGNALING GENES IN BREAST TUMORS WITH METASTASIS
by: N. V. Litviakov, et al.
Published: (2020-07-01)

Prediction of Therapeutic Response and Prognosis in Ovarian Cancer Patients With Plasma Circulating Biomarkers
by: Haixia Cheng, et al.
Published: (2025-08-01)

A catalog of numerical centrosome defects in epithelial ovarian cancers
by: Jean‐Philippe Morretton, et al.
Published: (2022-09-01)

Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers
by: Maria Teresa De Angelis, et al.
Published: (2025-08-01)

Prevalence and impact of molecular variation in the three-prime repair exonuclease 1 TREX1 and its implications for oncology
by: Marwa Shekfeh, et al.
Published: (2025-06-01)

VIMENTIN EXPRESSION IN HUMAN CELL LINES OF EPITHELIAL TUMORS
by: T. A. Bogush, et al.
Published: (2018-07-01)

Deciphering the heterogeneity of epithelial cells in pancreatic ductal adenocarcinoma: implications for metastasis and immune evasion
by: Jie Liu, et al.
Published: (2025-04-01)

Cancer phylogenetic tree inference at scale from 1000s of single cell genomes
by: Salehi, Sohrab, et al.
Published: (2023-07-01)

Despicable role of epithelial–mesenchymal transition in breast cancer metastasis: Exhibiting de novo restorative regimens
by: Paras Famta, et al.
Published: (2025-01-01)

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures
by: Nicholas A Graham, et al.
Published: (2017-02-01)

SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
by: Diane Zhang, et al.
Published: (2025-05-01)

Comparison of real-time PCR and nCounter NanoString techniques to validate copy number alterations in oral cancer
by: Rinal Chavda, et al.
Published: (2025-07-01)

Genetic Alterations in HER2-Positive and Equivocal Breast Cancer by Immunohistochemistry
by: Tsai YF, et al.
Published: (2025-03-01)

Cross‐Sectional Analysis of Metabolic Tumor Burden Detected by F‐18 FDG PET/CT and Circulating Tumor DNA in Advanced Breast Cancer
by: Recep Halit Tokac, et al.
Published: (2025-08-01)

CNA landscape of HER2-negative breast cancer during administration of taxane-containing schemes of neoadjuvant chemotherapy
by: M. K. Ibragimova, et al.
Published: (2025-04-01)

Lessons from the INSEMA trial: is sentinel lymph node biopsy in early-stage breast cancer stepping off the stage?
by: Xiaoyan Chen, et al.
Published: (2025-04-01)

Characterization of RNF144B and PPP2R2A identified by a novel approach using TCGA data in ovarian cancer
by: P. Manasa, et al.
Published: (2025-02-01)

KRAS amplification in colorectal cancer: correlations with clinicopathological features and prognosis in patients and prediction of response to targeted therapy
by: Xuanhua Yang, et al.
Published: (2025-07-01)

Classification of pediatric soft and bone sarcomas using DNA methylation-based profiling
by: Felipe Luz Torres Silva, et al.
Published: (2024-11-01)

Artemisia cinsinin iki türünün Artemisia fragrans Willd., A.absinthium L. karyolojik incelenmesi ve karyotip analizi
by: Ali Nazırzadeh, et al.
Published: (2009-01-01)

Genetic variations in morphology, chromosome number, and physiology of backcross progeny of the triploid hybrid clone ‘Beilinxiongzhu 1#’
by: Yaru Sang, et al.
Published: (2024-11-01)

Copy number normalization distinguishes differential signals driven by copy number differences in ATAC-seq and ChIP-seq
by: Dingwen Su, et al.
Published: (2025-03-01)

Redefining conservative mastectomy: the evolution of surgical techniques
by: Lorenzo Scardina, et al.
Published: (2025-03-01)

The regulatory effect of CoL10A1 to the intracranial vascular invasion and cell proliferation in breast cancer via EMT pathway
by: Xiaoyin Wang, et al.
Published: (2025-04-01)

Next-Generation Sequencing–Based Molecular Profiling of Conjunctival Squamous Cell Carcinoma and Its Potential Application for Therapy
by: Hakan Demirci, MD, et al.
Published: (2025-09-01)

Spectrum of Flat Epithelial Atypia in Breast Lesions
by: Nazish Jaffar, et al.
Published: (2023-10-01)

Outcomes of breast cancer management from an Urban specialist breast center in South India
by: Naga Amulya Mullapudi, et al.
Published: (2019-01-01)

Echinochrome A inhibits epithelial–mesenchymal transition and induces cell death mediated by DNA damage in human triple-negative breast cancer cells
by: Soon Yong Park, et al.
Published: (2025-10-01)

Landscape of metabolic alterations and treatment strategies in breast cancer
by: Xiujuan Wu, et al.
Published: (2025-09-01)

The “Culture” of Organs: A Holistic Theory on the Origins of the Cancer Tissue Environment
by: Robert D. Rehnke
Published: (2024-12-01)

Sodium butyrate and sodium propionate inhibit breast cancer cell migration and invasion through regulation of epithelial-to-mesenchymal transition and suppression of MEK/ERK signaling pathway
by: Dania Mahmoud Kharazi, et al.
Published: (2025-03-01)

Obesity-driven oleoylcarnitine accumulation in tumor microenvironment promotes breast cancer metastasis-like phenotype
by: Chao Chen, et al.
Published: (2025-04-01)

Comprehensive Analysis of Oncogenic Somatic Alterations of Mismatch Repair Gene in Breast Cancer Patients
by: Yin Yan, et al.
Published: (2025-04-01)

Analysis of surgical margins in breast cancer patients undergoing mastectomy in Tanzania
by: Nashivai Kivuyo, et al.
Published: (2025-08-01)

The diagnostic and therapeutic potential of exosomal proteins in breast cancer
by: A. A. Shefer, et al.
Published: (2023-07-01)