A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review

Atrial myxoma is the most common primary benign tumor of the heart, with over 75% occurring in the left atrium. The migration of myxoma cells can lead to rare neurological complications such as intracranial aneurysms, embolic strokes, and arteriovenous malformations. The most common neurological man...

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Main Authors: Min Xia, Yi Wang, Xuefeng An, Yufeng Huang, Ke Wei, Jia Zhou, Kun Li, Guojie Yao, He Huang
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605251333690
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author Min Xia
Yi Wang
Xuefeng An
Yufeng Huang
Ke Wei
Jia Zhou
Kun Li
Guojie Yao
He Huang
author_facet Min Xia
Yi Wang
Xuefeng An
Yufeng Huang
Ke Wei
Jia Zhou
Kun Li
Guojie Yao
He Huang
author_sort Min Xia
collection DOAJ
description Atrial myxoma is the most common primary benign tumor of the heart, with over 75% occurring in the left atrium. The migration of myxoma cells can lead to rare neurological complications such as intracranial aneurysms, embolic strokes, and arteriovenous malformations. The most common neurological manifestations in such patients include seizures, nonspecific headaches, and cerebrovascular events. Herein, we present a rare case of a middle-aged man in his early 50s with metastatic myxomatous multiple fusiform aneurysms, who initially presented with the clinical manifestation of intracerebral hemorrhage. The patient underwent atrial myxoma resection, whereas the intracranial multiple fusiform aneurysms were managed conservatively. Four years later, digital subtraction angiography revealed progressive enlargement of the aneurysm in the A3 segment of the left anterior cerebral artery. We present the pathological report of the atrial myxoma and imaging findings showing the changes in the aneurysms, along with a review and summary of the relevant literature. This report offers new insights into treatment options for cases of atrial myxoma complicated with intracranial multiple aneurysms. This is the first reported case of a male patient in China presenting with intracerebral hemorrhage as the initial manifestation of atrial myxoma combined with multiple fusiform aneurysms.
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issn 1473-2300
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publishDate 2025-04-01
publisher SAGE Publishing
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spelling doaj-art-c7ea7dd1a0074b8e970b7ff773b6c25c2025-08-20T02:56:02ZengSAGE PublishingJournal of International Medical Research1473-23002025-04-015310.1177/03000605251333690A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature reviewMin XiaYi WangXuefeng AnYufeng HuangKe WeiJia ZhouKun LiGuojie YaoHe HuangAtrial myxoma is the most common primary benign tumor of the heart, with over 75% occurring in the left atrium. The migration of myxoma cells can lead to rare neurological complications such as intracranial aneurysms, embolic strokes, and arteriovenous malformations. The most common neurological manifestations in such patients include seizures, nonspecific headaches, and cerebrovascular events. Herein, we present a rare case of a middle-aged man in his early 50s with metastatic myxomatous multiple fusiform aneurysms, who initially presented with the clinical manifestation of intracerebral hemorrhage. The patient underwent atrial myxoma resection, whereas the intracranial multiple fusiform aneurysms were managed conservatively. Four years later, digital subtraction angiography revealed progressive enlargement of the aneurysm in the A3 segment of the left anterior cerebral artery. We present the pathological report of the atrial myxoma and imaging findings showing the changes in the aneurysms, along with a review and summary of the relevant literature. This report offers new insights into treatment options for cases of atrial myxoma complicated with intracranial multiple aneurysms. This is the first reported case of a male patient in China presenting with intracerebral hemorrhage as the initial manifestation of atrial myxoma combined with multiple fusiform aneurysms.https://doi.org/10.1177/03000605251333690
spellingShingle Min Xia
Yi Wang
Xuefeng An
Yufeng Huang
Ke Wei
Jia Zhou
Kun Li
Guojie Yao
He Huang
A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
Journal of International Medical Research
title A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
title_full A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
title_fullStr A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
title_full_unstemmed A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
title_short A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review
title_sort male patient with atrial myxoma and multiple metastatic intracranial aneurysms a case report and literature review
url https://doi.org/10.1177/03000605251333690
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