A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging
A new Schiff base rhodamine 6G-indole-conjugated (RIC) probe with amine groups was synthesized for the highly sensitive and selective detection of Fe3+ ions. RIC showed selectivity for Fe3+ with minimal interference from 14 other metal ions. The detection limit was 40 nM. Density functional theory (...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-05-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625002115 |
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| author | Bao-Long Hou Wenyu Li Ruirui Feng Xiumei Yang Jianli Liu Cuiling Wang |
| author_facet | Bao-Long Hou Wenyu Li Ruirui Feng Xiumei Yang Jianli Liu Cuiling Wang |
| author_sort | Bao-Long Hou |
| collection | DOAJ |
| description | A new Schiff base rhodamine 6G-indole-conjugated (RIC) probe with amine groups was synthesized for the highly sensitive and selective detection of Fe3+ ions. RIC showed selectivity for Fe3+ with minimal interference from 14 other metal ions. The detection limit was 40 nM. Density functional theory (DFT) was used to predict the orbital electron distribution and molecular geometry of the RIC-Fe3+ complex. Moreover, confocal laser scanning microscopy was employed to confirm the effectiveness of RIC for detecting Fe3+ in living cells. Additionally, RIC proved effective in detecting Fe3+ in aqueous samples, with favorable relative recovery and standard deviations, thus offering a new method for Fe3+ detection in practical applications. |
| format | Article |
| id | doaj-art-c7c912cbb078409fa0e2a27266e366c1 |
| institution | DOAJ |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-c7c912cbb078409fa0e2a27266e366c12025-08-20T03:10:42ZengElsevierResults in Chemistry2211-71562025-05-011510222810.1016/j.rechem.2025.102228A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imagingBao-Long Hou0Wenyu Li1Ruirui Feng2Xiumei Yang3Jianli Liu4Cuiling Wang5Shaanxi Collaborative Innovation Center of Chinese Medicine Resources Industrialization, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi Innovative Drug Research Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, ChinaLaboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, ChinaLaboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, ChinaLaboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, ChinaLaboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China; Xi'an Peihua University, Xi'an 710125, ChinaLaboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China; Corresponding author at: Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710069, China.A new Schiff base rhodamine 6G-indole-conjugated (RIC) probe with amine groups was synthesized for the highly sensitive and selective detection of Fe3+ ions. RIC showed selectivity for Fe3+ with minimal interference from 14 other metal ions. The detection limit was 40 nM. Density functional theory (DFT) was used to predict the orbital electron distribution and molecular geometry of the RIC-Fe3+ complex. Moreover, confocal laser scanning microscopy was employed to confirm the effectiveness of RIC for detecting Fe3+ in living cells. Additionally, RIC proved effective in detecting Fe3+ in aqueous samples, with favorable relative recovery and standard deviations, thus offering a new method for Fe3+ detection in practical applications.http://www.sciencedirect.com/science/article/pii/S2211715625002115Fluorescent probeRhodamine derivativeFe3+ detectionCellular imaging |
| spellingShingle | Bao-Long Hou Wenyu Li Ruirui Feng Xiumei Yang Jianli Liu Cuiling Wang A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging Results in Chemistry Fluorescent probe Rhodamine derivative Fe3+ detection Cellular imaging |
| title | A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging |
| title_full | A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging |
| title_fullStr | A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging |
| title_full_unstemmed | A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging |
| title_short | A novel rhodamine 6G-based chemosensor for Fe3+ detection in water samples and cellular imaging |
| title_sort | novel rhodamine 6g based chemosensor for fe3 detection in water samples and cellular imaging |
| topic | Fluorescent probe Rhodamine derivative Fe3+ detection Cellular imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625002115 |
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