Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series
Spinal cord transcutaneous stimulation (scTS) offers a promising approach to enhance cardiovascular regulation in individuals with a high-level spinal cord injury (SCI), addressing the challenges of unstable blood pressure (BP) and the accompanying hypo- and hypertensive events. While scTS offers fl...
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| Format: | Article |
| Language: | English |
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Mary Ann Liebert
2024-11-01
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| Series: | Neurotrauma Reports |
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| Online Access: | https://www.liebertpub.com/doi/10.1089/neur.2024.0066 |
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| author | Einat Engel-Haber Akhil Bheemreddy Mehmed Bugrahan Bayram Manikandan Ravi Fan Zhang Haiyan Su Steven Kirshblum Gail F. Forrest |
| author_facet | Einat Engel-Haber Akhil Bheemreddy Mehmed Bugrahan Bayram Manikandan Ravi Fan Zhang Haiyan Su Steven Kirshblum Gail F. Forrest |
| author_sort | Einat Engel-Haber |
| collection | DOAJ |
| description | Spinal cord transcutaneous stimulation (scTS) offers a promising approach to enhance cardiovascular regulation in individuals with a high-level spinal cord injury (SCI), addressing the challenges of unstable blood pressure (BP) and the accompanying hypo- and hypertensive events. While scTS offers flexibility in stimulation locations, it also leads to significant variability and lack of validation in stimulation sites utilized by studies. Our study presents findings from a case series involving eight individuals with chronic cervical SCI, examining the hemodynamic effects of scTS applied in different vertebral locations, spanning from high cervical to sacral regions. Stimulation of the lumbosacral vertebrae region (L1/2, S1/2, and also including T11/12) significantly elevated BP, unlike cervical or upper thoracic stimulation. The observed trend, which remained consistent across different participants, highlights the promising role of lumbosacral stimulation in neuromodulating BP. |
| format | Article |
| id | doaj-art-c7b98685676345fdaf3308cea8026f71 |
| institution | OA Journals |
| issn | 2689-288X |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Neurotrauma Reports |
| spelling | doaj-art-c7b98685676345fdaf3308cea8026f712025-08-20T02:30:55ZengMary Ann LiebertNeurotrauma Reports2689-288X2024-11-015184585610.1089/neur.2024.0066Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case SeriesEinat Engel-Haber0Akhil Bheemreddy1Mehmed Bugrahan Bayram2Manikandan Ravi3Fan Zhang4Haiyan Su5Steven Kirshblum6Gail F. Forrest7Kessler Foundation, West Orange, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.School of Computing, Montclair State University, Montclair, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.Kessler Foundation, West Orange, New Jersey, USA.Spinal cord transcutaneous stimulation (scTS) offers a promising approach to enhance cardiovascular regulation in individuals with a high-level spinal cord injury (SCI), addressing the challenges of unstable blood pressure (BP) and the accompanying hypo- and hypertensive events. While scTS offers flexibility in stimulation locations, it also leads to significant variability and lack of validation in stimulation sites utilized by studies. Our study presents findings from a case series involving eight individuals with chronic cervical SCI, examining the hemodynamic effects of scTS applied in different vertebral locations, spanning from high cervical to sacral regions. Stimulation of the lumbosacral vertebrae region (L1/2, S1/2, and also including T11/12) significantly elevated BP, unlike cervical or upper thoracic stimulation. The observed trend, which remained consistent across different participants, highlights the promising role of lumbosacral stimulation in neuromodulating BP.https://www.liebertpub.com/doi/10.1089/neur.2024.0066blood pressurecardiovascularmappingspinal cord injuryspinal cord stimulationspinal cord transcutaneous stimulation |
| spellingShingle | Einat Engel-Haber Akhil Bheemreddy Mehmed Bugrahan Bayram Manikandan Ravi Fan Zhang Haiyan Su Steven Kirshblum Gail F. Forrest Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series Neurotrauma Reports blood pressure cardiovascular mapping spinal cord injury spinal cord stimulation spinal cord transcutaneous stimulation |
| title | Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series |
| title_full | Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series |
| title_fullStr | Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series |
| title_full_unstemmed | Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series |
| title_short | Neuromodulation in Spinal Cord Injury Using Transcutaneous Spinal Stimulation—Mapping for a Blood Pressure Response: A Case Series |
| title_sort | neuromodulation in spinal cord injury using transcutaneous spinal stimulation mapping for a blood pressure response a case series |
| topic | blood pressure cardiovascular mapping spinal cord injury spinal cord stimulation spinal cord transcutaneous stimulation |
| url | https://www.liebertpub.com/doi/10.1089/neur.2024.0066 |
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