Successful surgical management of mesenteric inflammatory veno-occlusive disease

Abstract Background The term “mesenteric inflammatory veno-occlusive disease (MIVOD)” is used to describe an ischemic injury resulting from phlebitis or venulitis that affects the bowel or mesentery in the absence of arteritis. MIVOD is difficult to diagnose because of its rarity and frequent confus...

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Main Authors: Keiji Matsuda, Yojiro Hashiguchi, Yoshinao Kikuchi, Kentaro Asako, Kohei Ohno, Yuka Okada, Takahiro Yagi, Mitsuo Tsukamoto, Yoshihisa Fukushima, Ryu Shimada, Tsuyoshi Ozawa, Tamuro Hayama, Takeshi Tsuchiya, Keijiro Nozawa, Yuko Sasajima, Fukuo Kondo
Format: Article
Language:English
Published: Japan Surgical Society 2020-01-01
Series:Surgical Case Reports
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Online Access:https://doi.org/10.1186/s40792-020-0796-1
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author Keiji Matsuda
Yojiro Hashiguchi
Yoshinao Kikuchi
Kentaro Asako
Kohei Ohno
Yuka Okada
Takahiro Yagi
Mitsuo Tsukamoto
Yoshihisa Fukushima
Ryu Shimada
Tsuyoshi Ozawa
Tamuro Hayama
Takeshi Tsuchiya
Keijiro Nozawa
Yuko Sasajima
Fukuo Kondo
author_facet Keiji Matsuda
Yojiro Hashiguchi
Yoshinao Kikuchi
Kentaro Asako
Kohei Ohno
Yuka Okada
Takahiro Yagi
Mitsuo Tsukamoto
Yoshihisa Fukushima
Ryu Shimada
Tsuyoshi Ozawa
Tamuro Hayama
Takeshi Tsuchiya
Keijiro Nozawa
Yuko Sasajima
Fukuo Kondo
author_sort Keiji Matsuda
collection DOAJ
description Abstract Background The term “mesenteric inflammatory veno-occlusive disease (MIVOD)” is used to describe an ischemic injury resulting from phlebitis or venulitis that affects the bowel or mesentery in the absence of arteritis. MIVOD is difficult to diagnose because of its rarity and frequent confusion with other diseases. The incidence and etiology of MIVOD remain unclear; only a few cases have been reported. We describe a case of the successful surgical management of a patient with MIVOD with characteristic images. Case presentation A 65-year-old Japanese man visited a hospital with the chief complaint of abdominal pain in January 2018. CT showed edema and thickening of the intestinal wall from the descending colon to the rectum. The patient was admitted to the hospital. Suspected diagnoses were enteritis, ulcerative colitis, amyloidosis, vasculitis, malignant lymphoma, and venous thrombus, but no definitive diagnosis was obtained. The patient was transferred to our hospital for the treatment of stenosis (located from the descending colon to the rectum) and bowel obstruction. An emergency transverse colostomy was performed. The sigmoid colon and mesentery were too rigid and edematous to resect. Colonic hemorrhage occurred 2 weeks after the surgery. With radiology intervention, coiling for the arteriovenous fistula in the descending colon was performed, and hemostasis was obtained. A colonoscopy at 6 months post-surgery showed neither ulceration nor stenosis in the rectum, indicating that the rectum could be preserved in the next surgery. However, severe stenosis in the descending and sigmoid colon remained unchanged. Ten months after the transverse colostomy, we performed a subtotal colectomy and ileorectal anastomosis, and an ileostomy was created. The sigmoid colon and mesentery were not so rigid compared to the first surgery’s findings, and we were able to resect intestine and mesentery. Histopathology revealed phlebitis and venulitis, fibrinoid necrosis, and normal arteries, meeting the diagnostic criteria for MIVOD. Postoperatively, the patient showed no recurrence for 8 months. Conclusion Clinicians should consider MIVOD when examining a patient with intestinal ischemia. When MIVOD is suspected, the patient is indicated for surgery based on an accurate diagnosis and good prognosis.
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spelling doaj-art-c7b62e02bf214b0bbc9b5c1cfcbcc8932025-08-20T03:20:14ZengJapan Surgical SocietySurgical Case Reports2198-77932020-01-01611910.1186/s40792-020-0796-1Successful surgical management of mesenteric inflammatory veno-occlusive diseaseKeiji Matsuda0Yojiro Hashiguchi1Yoshinao Kikuchi2Kentaro Asako3Kohei Ohno4Yuka Okada5Takahiro Yagi6Mitsuo Tsukamoto7Yoshihisa Fukushima8Ryu Shimada9Tsuyoshi Ozawa10Tamuro Hayama11Takeshi Tsuchiya12Keijiro Nozawa13Yuko Sasajima14Fukuo Kondo15Department of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Pathology, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Surgery, Teikyo University School of MedicineDepartment of Pathology, Teikyo University School of MedicineDepartment of Pathology, Teikyo University School of MedicineAbstract Background The term “mesenteric inflammatory veno-occlusive disease (MIVOD)” is used to describe an ischemic injury resulting from phlebitis or venulitis that affects the bowel or mesentery in the absence of arteritis. MIVOD is difficult to diagnose because of its rarity and frequent confusion with other diseases. The incidence and etiology of MIVOD remain unclear; only a few cases have been reported. We describe a case of the successful surgical management of a patient with MIVOD with characteristic images. Case presentation A 65-year-old Japanese man visited a hospital with the chief complaint of abdominal pain in January 2018. CT showed edema and thickening of the intestinal wall from the descending colon to the rectum. The patient was admitted to the hospital. Suspected diagnoses were enteritis, ulcerative colitis, amyloidosis, vasculitis, malignant lymphoma, and venous thrombus, but no definitive diagnosis was obtained. The patient was transferred to our hospital for the treatment of stenosis (located from the descending colon to the rectum) and bowel obstruction. An emergency transverse colostomy was performed. The sigmoid colon and mesentery were too rigid and edematous to resect. Colonic hemorrhage occurred 2 weeks after the surgery. With radiology intervention, coiling for the arteriovenous fistula in the descending colon was performed, and hemostasis was obtained. A colonoscopy at 6 months post-surgery showed neither ulceration nor stenosis in the rectum, indicating that the rectum could be preserved in the next surgery. However, severe stenosis in the descending and sigmoid colon remained unchanged. Ten months after the transverse colostomy, we performed a subtotal colectomy and ileorectal anastomosis, and an ileostomy was created. The sigmoid colon and mesentery were not so rigid compared to the first surgery’s findings, and we were able to resect intestine and mesentery. Histopathology revealed phlebitis and venulitis, fibrinoid necrosis, and normal arteries, meeting the diagnostic criteria for MIVOD. Postoperatively, the patient showed no recurrence for 8 months. Conclusion Clinicians should consider MIVOD when examining a patient with intestinal ischemia. When MIVOD is suspected, the patient is indicated for surgery based on an accurate diagnosis and good prognosis.https://doi.org/10.1186/s40792-020-0796-1Mesenteric inflammatory veno-occlusive disorderSurgeryStenosisBleeding
spellingShingle Keiji Matsuda
Yojiro Hashiguchi
Yoshinao Kikuchi
Kentaro Asako
Kohei Ohno
Yuka Okada
Takahiro Yagi
Mitsuo Tsukamoto
Yoshihisa Fukushima
Ryu Shimada
Tsuyoshi Ozawa
Tamuro Hayama
Takeshi Tsuchiya
Keijiro Nozawa
Yuko Sasajima
Fukuo Kondo
Successful surgical management of mesenteric inflammatory veno-occlusive disease
Surgical Case Reports
Mesenteric inflammatory veno-occlusive disorder
Surgery
Stenosis
Bleeding
title Successful surgical management of mesenteric inflammatory veno-occlusive disease
title_full Successful surgical management of mesenteric inflammatory veno-occlusive disease
title_fullStr Successful surgical management of mesenteric inflammatory veno-occlusive disease
title_full_unstemmed Successful surgical management of mesenteric inflammatory veno-occlusive disease
title_short Successful surgical management of mesenteric inflammatory veno-occlusive disease
title_sort successful surgical management of mesenteric inflammatory veno occlusive disease
topic Mesenteric inflammatory veno-occlusive disorder
Surgery
Stenosis
Bleeding
url https://doi.org/10.1186/s40792-020-0796-1
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