Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease
To date, the etiology and pathogenesis of Crohn’s disease (CD) have not been fully elucidated. It is widely accepted that genetic, immune, and environment factors are closely related to the development of CD. As an important defensive line for human body against the environment, intestinal mucosa is...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/9686238 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849473385632890880 |
|---|---|
| author | Kuan Wang Lu-yi Wu Chuan-zi Dou Xin Guan Huan-gan Wu Hui-rong Liu |
| author_facet | Kuan Wang Lu-yi Wu Chuan-zi Dou Xin Guan Huan-gan Wu Hui-rong Liu |
| author_sort | Kuan Wang |
| collection | DOAJ |
| description | To date, the etiology and pathogenesis of Crohn’s disease (CD) have not been fully elucidated. It is widely accepted that genetic, immune, and environment factors are closely related to the development of CD. As an important defensive line for human body against the environment, intestinal mucosa is able to protect the homeostasis of gut bacteria and alleviate the intestinal inflammatory and immune response. It is evident that the dysfunction of intestinal mucosa barriers plays a crucial role in CD initiation and development. Yet researches are insufficient on intestinal mucosal barrier’s action in the prevention of CD onset. This article summarizes the research advances about the correlations between the disorders of intestinal mucosal barriers and CD. |
| format | Article |
| id | doaj-art-c7b08f998bd44fa0959f1c87e2e4ebf8 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-c7b08f998bd44fa0959f1c87e2e4ebf82025-08-20T03:24:10ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/96862389686238Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s DiseaseKuan Wang0Lu-yi Wu1Chuan-zi Dou2Xin Guan3Huan-gan Wu4Hui-rong Liu5Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, ChinaShanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, ChinaShanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, ChinaShanghai Shuguang Hospital Affiliated with Shanghai University of Traditional Chinese Medicine, Shanghai 201203, ChinaShanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, ChinaShanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai 200030, ChinaTo date, the etiology and pathogenesis of Crohn’s disease (CD) have not been fully elucidated. It is widely accepted that genetic, immune, and environment factors are closely related to the development of CD. As an important defensive line for human body against the environment, intestinal mucosa is able to protect the homeostasis of gut bacteria and alleviate the intestinal inflammatory and immune response. It is evident that the dysfunction of intestinal mucosa barriers plays a crucial role in CD initiation and development. Yet researches are insufficient on intestinal mucosal barrier’s action in the prevention of CD onset. This article summarizes the research advances about the correlations between the disorders of intestinal mucosal barriers and CD.http://dx.doi.org/10.1155/2016/9686238 |
| spellingShingle | Kuan Wang Lu-yi Wu Chuan-zi Dou Xin Guan Huan-gan Wu Hui-rong Liu Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease Gastroenterology Research and Practice |
| title | Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease |
| title_full | Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease |
| title_fullStr | Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease |
| title_full_unstemmed | Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease |
| title_short | Research Advance in Intestinal Mucosal Barrier and Pathogenesis of Crohn’s Disease |
| title_sort | research advance in intestinal mucosal barrier and pathogenesis of crohn s disease |
| url | http://dx.doi.org/10.1155/2016/9686238 |
| work_keys_str_mv | AT kuanwang researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease AT luyiwu researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease AT chuanzidou researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease AT xinguan researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease AT huanganwu researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease AT huirongliu researchadvanceinintestinalmucosalbarrierandpathogenesisofcrohnsdisease |