Supplemental nucleus pulposus allograft in patients with lumbar discogenic pain: results of a prospective feasibility study

Supplemental nucleus pulposus allograft in patients with lumbar discogenic pain: results of a prospective feasibility study

Abstract Background Degeneration of the intervertebral disc is a significant source of chronic axial low back pain. Direct supplementation of degenerated nucleus pulposis (NP) tissue with intradiscally delivered allogeneic NP represents an opportunity to bridge the treatment gap between failed conse...

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Main Authors: Douglas P. Beall, Timothy T. Davis, Kasra Amirdelfan, Ramana K. Naidu, Michael J. DePalma, Shrif Costandi, Edward S. Yoon, Jacob W. Fleming, Jon E. Block, Nagy Mekhail
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Nucleus pulposus
Allograft
Discogenic
Back pain
Intradiscal
Degenerative disc disease
Online Access:https://doi.org/10.1186/s12891-025-08701-0
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