Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?

Scurvy, a condition caused by a deficiency in ascorbic acid, is often considered an outdated, textbook disease, largely forgotten in the 21st century. However, recent reports indicate a rise in cases, particularly among individuals with risk factors for nutritional deficiencies or those with specifi...

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Main Authors: Preeyanikaa Logonathan, Nurhidayah Muhd Noor, Aminah Marsom
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Child and Adolescent Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/frcha.2025.1600861/full
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author Preeyanikaa Logonathan
Nurhidayah Muhd Noor
Aminah Marsom
author_facet Preeyanikaa Logonathan
Nurhidayah Muhd Noor
Aminah Marsom
author_sort Preeyanikaa Logonathan
collection DOAJ
description Scurvy, a condition caused by a deficiency in ascorbic acid, is often considered an outdated, textbook disease, largely forgotten in the 21st century. However, recent reports indicate a rise in cases, particularly among individuals with risk factors for nutritional deficiencies or those with specific dietary habits. These cases are frequently misdiagnosed, leading to a series of unnecessary tests that could be avoided with a thorough assessment of dietary intake. In this report, we present the case of a 10-year-old with autism spectrum disorder (ASD) and a selective eating pattern, who presented with a limping gait, tenderness in the right calf, and significant weight loss. A skin examination revealed multiple perifollicular hemorrhages with corkscrew-shaped hair, as well as localized erythematous and hypertrophic gingiva in all four quadrants. Based on clinical findings, scurvy was suspected, and vitamin C supplementation was initiated both for diagnostic and therapeutic purposes. The diagnosis was confirmed when serum vitamin C levels were found to be critically low (5 µmol/L, normal range: 28–120 µmol/L). The patient's response to vitamin C was impressive, with complete gingival healing and noticeable weight gain within three weeks. Although scurvy is often thought of as an ancient disease, it has seen a resurgence, posing diagnostic challenges due to its diverse clinical manifestations. Early diagnosis, along with appropriate intervention and dietary changes, can lead to an excellent prognosis for individuals with scurvy.
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spelling doaj-art-c7aa31e321f54d339a61945d30cfc7c22025-08-20T03:12:43ZengFrontiers Media S.A.Frontiers in Child and Adolescent Psychiatry2813-45402025-07-01410.3389/frcha.2025.16008611600861Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?Preeyanikaa LogonathanNurhidayah Muhd NoorAminah MarsomScurvy, a condition caused by a deficiency in ascorbic acid, is often considered an outdated, textbook disease, largely forgotten in the 21st century. However, recent reports indicate a rise in cases, particularly among individuals with risk factors for nutritional deficiencies or those with specific dietary habits. These cases are frequently misdiagnosed, leading to a series of unnecessary tests that could be avoided with a thorough assessment of dietary intake. In this report, we present the case of a 10-year-old with autism spectrum disorder (ASD) and a selective eating pattern, who presented with a limping gait, tenderness in the right calf, and significant weight loss. A skin examination revealed multiple perifollicular hemorrhages with corkscrew-shaped hair, as well as localized erythematous and hypertrophic gingiva in all four quadrants. Based on clinical findings, scurvy was suspected, and vitamin C supplementation was initiated both for diagnostic and therapeutic purposes. The diagnosis was confirmed when serum vitamin C levels were found to be critically low (5 µmol/L, normal range: 28–120 µmol/L). The patient's response to vitamin C was impressive, with complete gingival healing and noticeable weight gain within three weeks. Although scurvy is often thought of as an ancient disease, it has seen a resurgence, posing diagnostic challenges due to its diverse clinical manifestations. Early diagnosis, along with appropriate intervention and dietary changes, can lead to an excellent prognosis for individuals with scurvy.https://www.frontiersin.org/articles/10.3389/frcha.2025.1600861/fullautismeating behaviourlimpinggingival swellingscurvy
spellingShingle Preeyanikaa Logonathan
Nurhidayah Muhd Noor
Aminah Marsom
Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
Frontiers in Child and Adolescent Psychiatry
autism
eating behaviour
limping
gingival swelling
scurvy
title Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
title_full Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
title_fullStr Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
title_full_unstemmed Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
title_short Case Report: Autistic child with restrictive eating behaviour, limping gait and erythematous gingival mass-scurvy?
title_sort case report autistic child with restrictive eating behaviour limping gait and erythematous gingival mass scurvy
topic autism
eating behaviour
limping
gingival swelling
scurvy
url https://www.frontiersin.org/articles/10.3389/frcha.2025.1600861/full
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AT aminahmarsom casereportautisticchildwithrestrictiveeatingbehaviourlimpinggaitanderythematousgingivalmassscurvy