Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles

The effects of yam powder (YP) on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products. Using wheat flour as the main ingredient, the effects of different YP substitution rat...

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Main Authors: Feng Jia, Zhihang Qiao, Lei Zeng, Zuchong Liu, Haifeng Li, Jikai Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Grain & Oil Science and Technology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590259825000342
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author Feng Jia
Zhihang Qiao
Lei Zeng
Zuchong Liu
Haifeng Li
Jikai Zhao
author_facet Feng Jia
Zhihang Qiao
Lei Zeng
Zuchong Liu
Haifeng Li
Jikai Zhao
author_sort Feng Jia
collection DOAJ
description The effects of yam powder (YP) on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products. Using wheat flour as the main ingredient, the effects of different YP substitution ratios (0, 5 %, 10 %, 15 %, 20 %, and 25 %) on polyphenolic content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging rate, and starch digestibility of the prepared noodles were analyzed in vitro. Additionally, the effects of YP water-soluble extracts, wheat flour noodles, and YP-enriched noodles (hereinafter, YP noodles) on inflammatory factors in vascular smooth muscle cells (VSMCs) treated by H2O2 (100 μM) were investigated. The results showed that YP had a substantial effect on polyphenolic content and DPPH free radical scavenging rate of wheat flour noodles, significantly increasing both values compared with those of the control group (P < 0.05). The polyphenolic content reached a maximum of 2.17 mg/g in noodles with 20 % YP substitution, whereas DPPH free radical scavenging rate reached a maximum of 42.10 % in noodles with 25 % YP substitution. With an increase in YP amount, both starch hydrolysis rate and rapidly digestible starch content of the noodles decreased gradually, whereas resistant starch content increased significantly. Moreover, 50, 100, and 200 μg/mL of water-soluble YP and YP noodle extracts had no significant effect on the viability of VSMCs, and high concentrations of YP and YP noodle extracts resulted in cell death. Both YP and noodle extracts also reduced the secretion levels of inflammatory factors IL-6 and TNF-α in H2O2-treated VSMCs. Overall, YP addition reduced starch digestibility, increased antioxidative activity, and effectively improved functional quality of noodles. This study provides reference for the research and development of health-benefiting anti-inflammatory foods.
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spelling doaj-art-c7a3dd3acad24efa93daea499fdcc8f22025-08-20T02:56:21ZengKeAi Communications Co., Ltd.Grain & Oil Science and Technology2590-25982025-09-018319219910.1016/j.gaost.2025.06.001Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodlesFeng Jia0Zhihang Qiao1Lei Zeng2Zuchong Liu3Haifeng Li4Jikai Zhao5School of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China; Corresponding author at: School of Biological Engineering, Henan University of Technology, Zhengzhou 450001, China.School of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaSchool of Biological Engineering, Henan University of Technology, Zhengzhou 450001, ChinaCarl and Melinda Helwig Department of Biological and Agricultural Engineering, Kansas State University, Manhattan, KS 66506, United StatesThe effects of yam powder (YP) on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products. Using wheat flour as the main ingredient, the effects of different YP substitution ratios (0, 5 %, 10 %, 15 %, 20 %, and 25 %) on polyphenolic content, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging rate, and starch digestibility of the prepared noodles were analyzed in vitro. Additionally, the effects of YP water-soluble extracts, wheat flour noodles, and YP-enriched noodles (hereinafter, YP noodles) on inflammatory factors in vascular smooth muscle cells (VSMCs) treated by H2O2 (100 μM) were investigated. The results showed that YP had a substantial effect on polyphenolic content and DPPH free radical scavenging rate of wheat flour noodles, significantly increasing both values compared with those of the control group (P < 0.05). The polyphenolic content reached a maximum of 2.17 mg/g in noodles with 20 % YP substitution, whereas DPPH free radical scavenging rate reached a maximum of 42.10 % in noodles with 25 % YP substitution. With an increase in YP amount, both starch hydrolysis rate and rapidly digestible starch content of the noodles decreased gradually, whereas resistant starch content increased significantly. Moreover, 50, 100, and 200 μg/mL of water-soluble YP and YP noodle extracts had no significant effect on the viability of VSMCs, and high concentrations of YP and YP noodle extracts resulted in cell death. Both YP and noodle extracts also reduced the secretion levels of inflammatory factors IL-6 and TNF-α in H2O2-treated VSMCs. Overall, YP addition reduced starch digestibility, increased antioxidative activity, and effectively improved functional quality of noodles. This study provides reference for the research and development of health-benefiting anti-inflammatory foods.http://www.sciencedirect.com/science/article/pii/S2590259825000342YamWheat flour noodlesVSMCsIL-6TNF-αDPPH
spellingShingle Feng Jia
Zhihang Qiao
Lei Zeng
Zuchong Liu
Haifeng Li
Jikai Zhao
Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
Grain & Oil Science and Technology
Yam
Wheat flour noodles
VSMCs
IL-6
TNF-α
DPPH
title Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
title_full Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
title_fullStr Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
title_full_unstemmed Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
title_short Exploration of in vitro digestive, antioxidative, and anti-inflammatory benefits of yam (Dioscorea rhizoma) powder-enriched noodles
title_sort exploration of in vitro digestive antioxidative and anti inflammatory benefits of yam dioscorea rhizoma powder enriched noodles
topic Yam
Wheat flour noodles
VSMCs
IL-6
TNF-α
DPPH
url http://www.sciencedirect.com/science/article/pii/S2590259825000342
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