The Protective Role of PGC-1α in Cystitis Glandularis: Mitigating Mitochondrial Injury and Inflammation

The Protective Role of PGC-1α in Cystitis Glandularis: Mitigating Mitochondrial Injury and Inflammation

Conclusions: The downregulation of PGC-1α suggests its potential as a molecular marker for the progression of CG. Targeting the PGC-1α signaling pathway may offer an effective therapeutic intervention for the clinical management of CG.

Saved in:

Bibliographic Details
Main Authors:	Min Chen, Yongbo Tang, Yue Fu, Haiwei Hu, Ende Cui, Zhouliang Wen, Wei Zhong, Jimin Su, Bo Ge
Format:	Article
Language:	English
Published:	Wiley 2024-01-01
Series:	International Journal of Clinical Practice
Online Access:	http://dx.doi.org/10.1155/ijcp/8164243
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A machine learning-based nomogram model for predicting the recurrence of cystitis glandularis
by: Xuhao Liu, et al.
Published: (2024-10-01)

Association between cystitis glandularis and bladder neck leiomyoma: A case report and literature review
by: Caixia Zhang, et al.
Published: (2025-03-01)

Cystitis glandularis due to Escherichia coli infection in a diabetic Miniature Schnauzer: a case report
by: J. P. Rey Amunategui, et al.
Published: (2025-01-01)

PGC-1α Promotes mitochondrial biosynthesis and energy metabolism of goose fatty liver
by: Jiahui Li, et al.
Published: (2025-01-01)

HDL Mimetics Enhances Mitochondrial Function via Stimulation of PGC1-α
by: Hang Zhang, et al.
Published: (2023-04-01)

Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation
by: Ruochen Che, et al.
Published: (2015-01-01)

Gpbar1-mediated SIRT1-PGC-1α axis maintains mitochondrial homeostasis and mitigates renal injury in obstructive jaundice
by: Mingchen Li, et al.
Published: (2025-07-01)

PGC1α regulates the mitochondrial metabolism response to cyclic stretch, which inhibits neointimal hyperplasia
by: Minwen Zou, et al.
Published: (2025-08-01)

Pyruvate kinase M2 activation maintains mitochondrial metabolism by regulating the interaction between HIF-1α and PGC-1α in diabetic kidney disease
by: Jimin Park, et al.
Published: (2025-07-01)

Caloric Restriction and the Nutrient-Sensing PGC-1α in Mitochondrial Homeostasis: New Perspectives in Neurodegeneration
by: Daniele Lettieri Barbato, et al.
Published: (2012-01-01)

Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation.
by: Kazuhiko Higashida, et al.
Published: (2013-07-01)

Transcriptional Regulation by Nuclear Corepressors and PGC-1α: Implications for Mitochondrial Quality Control and Insulin Sensitivity
by: Zhengtang Qi, et al.
Published: (2012-01-01)

Hypothermia Mitigates Renal Fibrosis Through the Upregulation of PGC-1α After Ischemia–Reperfusion Injury
by: Dabi Kim, et al.
Published: (2025-05-01)

Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice
by: Weilun Miao, et al.
Published: (2022-01-01)

1-Bromopropane induces mitochondrial damage and lipid metabolism imbalance in respiratory epithelial cells through the PGC-1α/PPARα pathway
by: Qiuyun Wu, et al.
Published: (2025-01-01)

PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells
by: Dante Miranda, et al.
Published: (2016-01-01)

CRAT downregulation promotes ovarian cancer progression by facilitating mitochondrial metabolism through decreasing the acetylation of PGC-1α
by: Zhen Zhang, et al.
Published: (2025-01-01)

Astragalin improved mitochondrial function through AMPK/PGC-1α pathway and alleviated renal injury in diabetic nephropathy
by: Yi Luo, et al.
Published: (2024-11-01)

Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.
by: Marc Liesa, et al.
Published: (2008-01-01)

SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway
by: Yanping Zhao, et al.
Published: (2025-03-01)

Astragaloside IV accelerates hematopoietic reconstruction by improving the AMPK/PGC1α-mediated mitochondrial function in hematopoietic stem cells
by: Ling Zhang, et al.
Published: (2025-04-01)

Mitochondria and PGC-1α in Aging and Age-Associated Diseases
by: Tina Wenz
Published: (2011-01-01)

Exercise-induced PGC-1α transcriptional factors in skeletal muscle
by: Suryun Jung, et al.
Published: (2014-12-01)

METTL3, an Independent Adverse Prognostic Factor for AML, Promotes the Development of AML by Modulating the PGC‐1α–MAPK Pathway and PGC‐1α–Antioxidant System Axis
by: Yuqian Tang, et al.
Published: (2025-04-01)

4-Octyl itaconate attenuates renal tubular injury in db/db mice by activating Nrf2 and promoting PGC-1α-mediated mitochondrial biogenesis
by: Muqing Shao, et al.
Published: (2024-12-01)

Role of PGC-1-alpha-associated Mitochondrial Biogenesis in Statin-induced Myotoxicity
by: M Panajatovic, et al.
Published: (2020-05-01)

MicroRNA-668 alleviates renal fibrosis through PPARα/PGC-1α pathway
by: Xinran Wang, et al.
Published: (2024-12-01)

PGC-1α activation to enhance macrophage immune function in mycobacterial infections.
by: Joel R Frandsen, et al.
Published: (2025-01-01)

Activation of spinal PGC-1α regulates microglial polarization through a feedback loop between ROS-mediated mitochondrial dysfunction and the NLRP3 inflammasome in neuropathic pain
by: Yanhua Chen, et al.
Published: (2025-07-01)

Resveratrol activates PGC-1α pathway via PRAKK1 to regulate mitochondrial biogenesis and alleviate inflammatory responses in bovine mammary epithelial cells
by: ChunLi Hu, et al.
Published: (2025-01-01)

High-dose vitamin C promotes mitochondrial biogenesis in HCT116 colorectal cancer cells by regulating the AMPK/PGC-1α signaling pathway
by: RuiYang Hong, et al.
Published: (2025-05-01)

SLC25A35 enhances fatty acid oxidation and mitochondrial biogenesis to promote the carcinogenesis and progression of hepatocellular carcinoma by upregulating PGC-1α
by: Heng-Chao Yu, et al.
Published: (2025-03-01)

Changes of PGC-1α/TFAM signaling pathway and mitochondrial dysfunction of renal tubular epithelial cells during sepsis-associated acute kidney injury
by: Xiao Zhen-meng, et al.
Published: (2021-01-01)

Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway
by: Runmei Zou, et al.
Published: (2023-01-01)

Engeletin Targets Mitochondrial Dysfunction to Attenuate Oxidative Stress and Experimental Colitis in Intestinal Epithelial Cells Through AMPK/SIRT1/PGC-1α Signaling
by: Jing Li, et al.
Published: (2025-04-01)

Maternal zinc alleviates tert-butyl hydroperoxide-induced mitochondrial oxidative stress on embryonic development involving the activation of Nrf2/PGC-1α pathway
by: Liang Huang, et al.
Published: (2023-04-01)

Neuron-specific isoform of PGC-1α regulates neuronal metabolism and brain aging
by: Dylan C. Souder, et al.
Published: (2025-02-01)

PEROXYSOME PROLIFERATOR-ACTIVATED RECEPTORS AND THEIR COACTIVATOR — PGC-1α — IN PHYSIOLOGY AND PATHOLOGY OF MYOCARDIUM
by: M. S. Rasin
Published: (2014-11-01)

Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential
by: Mi-bo Tang, et al.
Published: (2025-02-01)

Uncomplicated cystitis
by: Andy Gray
Published: (2002-03-01)