Bone marrow-derived mesenchymal stromal cells in necrotizing enterocolitis treatment: a narrative review

Bone marrow-derived mesenchymal stromal cells in necrotizing enterocolitis treatment: a narrative review

Necrotizing enterocolitis (NEC) presents a life-threatening intestinal emergency primarily affecting premature infants in neonatal intensive care units. This disease is a significant cause of morbidity and mortality in such newborns. NEC involves inflammation, bacterial overgrowth, and cell death af...

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Bibliographic Details
Main Authors: Andrea Tomaselli, Matteo Tripodi, Livia Provitera, Genny Raffaeli, Stefania Crippa, Ludovica Raymo, Carolina Vittoria Bronzoni, Ludovica Santi, Cristina Arribas, Monica Fumagalli, Stavros Polydoros Loukogeorgakis, Maria Ester Bernardo, Felipe Garrido, Giacomo Cavallaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pediatrics
Subjects:
necrotizing enterocolitis
bone marrow-derived mesenchymal stromal cells
toll-like receptor 4
exosomes
secretome
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1624236/full
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