Bone marrow-derived mesenchymal stromal cells in necrotizing enterocolitis treatment: a narrative review

Bone marrow-derived mesenchymal stromal cells in necrotizing enterocolitis treatment: a narrative review

Necrotizing enterocolitis (NEC) presents a life-threatening intestinal emergency primarily affecting premature infants in neonatal intensive care units. This disease is a significant cause of morbidity and mortality in such newborns. NEC involves inflammation, bacterial overgrowth, and cell death af...

Full description

Saved in:

Bibliographic Details
Main Authors:	Andrea Tomaselli, Matteo Tripodi, Livia Provitera, Genny Raffaeli, Stefania Crippa, Ludovica Raymo, Carolina Vittoria Bronzoni, Ludovica Santi, Cristina Arribas, Monica Fumagalli, Stavros Polydoros Loukogeorgakis, Maria Ester Bernardo, Felipe Garrido, Giacomo Cavallaro
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Pediatrics
Subjects:	necrotizing enterocolitis bone marrow-derived mesenchymal stromal cells toll-like receptor 4 exosomes secretome
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2025.1624236/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Gut Microbiota-Derived Metabolites and Their Role in the Pathogenesis of Necrotizing Enterocolitis in Preterm Infants: A Narrative Review
by: Livia Provitera, et al.
Published: (2024-10-01)

Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence
by: Nicola Alessio, et al.
Published: (2020-03-01)

A survey on the perception of health degree students on the use of Instagram and TikTok as learning tools
by: Silvia Garrido, et al.
Published: (2025-07-01)

The Ex-utero intrapartum treatment procedure: a narrative review
by: Michele Gaffuri, et al.
Published: (2025-07-01)

Dental pulp mesenchymal stem cell (DPSCs)-derived soluble factors, produced under hypoxic conditions, support angiogenesis via endothelial cell activation and generation of M2-like macrophages
by: Ludovica Barone, et al.
Published: (2024-11-01)

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics
by: Ayman M. Ibrahim, et al.
Published: (2025-08-01)

Tissue integrity and healing response in hypoestrogenic animal model treated by mesh implantation with addition of mesenchymal stem cell secretome
by: Tri Isyani Tungga Dewi, et al.
Published: (2025-01-01)

Characteristic Differences between Freeze-dried Tenogenic Secretomes and Freeze-dried Crude Secretomes of Mesenchymal Stem Cells under Hypoxic Conditions
by: Agus Kresnadi, et al.
Published: (2024-03-01)

Effectiveness of Stem Cell Secretomes in the Regeneration and Functional Recovery of Severed Nerves in Patients with Nerve Injuries: A Systematic Review
by: Endika Nevado-Sánchez, et al.
Published: (2025-03-01)

Proteomic analysis of hydrogen peroxide-treated human chondrocytes shows endoplasmic reticulum stress, cytoskeleton remodeling, and altered secretome composition
by: Thais Mingatos de Toledo, et al.
Published: (2025-06-01)

Resveratrol promotes secretion of wound healing related growth factors of mesenchymal stem cells originated from adult and fetal tissues
by: Cita R. S. Prakoeswa, et al.
Published: (2020-01-01)

Omic tools to study enzyme production from fungi in the Pleurotus genus
by: Maura Téllez-Téllez, et al.
Published: (2019-02-01)

Possibilities of MMSC secretome application for osteorepair stimulation: an experimental study
by: Kuznetsova M.A., et al.
Published: (2025-02-01)

An overview of stem cells and cell products involved in trauma injury
by: Pardis Saeedi, et al.
Published: (2025-06-01)

Among-population proteomic differences in Schistocephalus solidus based on excretory/secretory and total body protein predictions
by: Anni Wang, et al.
Published: (2025-05-01)

The Otoacoustic Emissions in the Universal Neonatal Hearing Screening: An Update on the European Data (2004 to 2024)
by: Stavros Hatzopoulos, et al.
Published: (2024-10-01)

Partecipazione alle primarie dell'Unione
by: Vittoria Cuturi, et al.
Published: (2006-06-01)

NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment
by: Beatrice Ghezzi, et al.
Published: (2025-07-01)

Hydrolytic Enzymes in the Secretome of the Mushrooms <i>P. eryngii</i> and <i>P. ostreatus</i>: A Comparison Between the Two Species
by: Tania Petraglia, et al.
Published: (2025-06-01)

Enhancing Wound Healing Through Secretome-Loaded 3D-Printed Biomaterials
by: Tithteeya Rattanachot, et al.
Published: (2025-06-01)

The Effect of Stem Cell Secretome on the Improvement of Diabetic Wound Recovery: A Systematic Review and Meta-Analysis of In Vivo Studies
by: Cecep Suhandi, MSc, et al.
Published: (2025-01-01)

Metformin pre-conditioning enhances the angiogenic ability of the secretome of dental pulp stem cells
by: Nezar Boreak, et al.
Published: (2021-08-01)

Method standardization of secretome production, collection, and characterization: New insights and challenges
by: Nivisti Singh, et al.
Published: (2025-06-01)

Investigating the Effect of Secretome Secreted from Adult Rat Kidney-Derived Stem Cells on the Expression of miR375, miR494 and Tissue Changes in Glycerol-Induced Acute Kidney Injury
by: Armita Valizadeh Gorji, et al.
Published: (2025-05-01)

Proteomic analysis of Trichoderma harzianum secretome and their role in the biosynthesis of zinc/iron oxide nanoparticles
by: Micaela B. Gallo, et al.
Published: (2025-01-01)

Effects of Adipose-Derived Mesenchymal Stem Cell-Secretome on Pyroptosis of Laparoscopic Hepatic Ischemia Reperfusion Injury in a Porcine Model
by: Yajun Ma, et al.
Published: (2025-05-01)

Müller cells and retinal angiogenesis: critical regulators in health and disease
by: Alan E. Medina-Arellano, et al.
Published: (2024-12-01)

Effect of Robusta Coffee Bean Extract as Immunoregulator on Dental Pulp Mesenchymal Stem Cells via Paracrine Pathway
by: Desi Sandra Sari, et al.
Published: (2025-02-01)

Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis
by: Filomena Napolitano, et al.
Published: (2025-02-01)

Predictive potential of combined secretomics and image-based morphometry as a non-invasive method for selecting implanting embryos
by: Andrea Palomar, et al.
Published: (2025-04-01)

Genome, transcriptome and secretome analyses of the antagonistic, yeast-like fungus Aureobasidium pullulans to identify potential biocontrol genes
by: Maria Paula Rueda-Mejia, et al.
Published: (2021-06-01)

Post-Insemination Infusion of Wharton’s Jelly Mesenchymal Stromal/Stem Cells-Derived Conditioned Medium: A Novel Approach for Improving Pregnancy Outcomes in Problem Mares
by: Chiara Del Prete, et al.
Published: (2025-05-01)

Early Hearing Interventions for Children with Hearing Loss in Africa: A 21-Year Scoping Review (2004–2025)
by: Stavros Hatzopoulos, et al.
Published: (2025-06-01)

Neural stem cell secretome: a secret key to unlocking the power of regeneration in the adult and aging brain
by: Soumia Abdellaoui, et al.
Published: (2025-01-01)

TISSUE REGENERATION AND ONCOGENESIS-SIMILARITIES AND DIFFERENCES
by: V. A. Tkachuk
Published: (2021-05-01)

Establishment of a Protocol for the Characterization of Secreted Biomolecules in Somatic Embryogenic Cultures of <i>Olea europaea</i> L.
by: Rita Pires, et al.
Published: (2025-03-01)

Shear Stress and Microbubble‐Mediated Modulation of Endothelial Cell Immunobiology
by: Elahe Memari, et al.
Published: (2025-04-01)

Topical Delivery of Mesenchymal Stem Cells “Secretomes” in Wound Repair
by: Indah Julianto, et al.
Published: (2017-05-01)

Secretome of human amniotic membrane stem cells promote recovery and testicular functions through modulating SIRT1/NRF2/TNF-α pathway in mice testicular torsion: An experimental study
by: Roghayeh Esfehani, et al.
Published: (2024-12-01)

Topical Delivery of Mesenchymal Stem Cells “Secretomes” in Wound Repair
by: Indah Julianto, et al.
Published: (2017-05-01)