Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report
Lung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 6...
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1524248/full |
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| author | Xue-Jiao Yang Yong-Juan Wu Jing-Zhong Wang Yu-Lan Zheng Xiao-Qi Li |
| author_facet | Xue-Jiao Yang Yong-Juan Wu Jing-Zhong Wang Yu-Lan Zheng Xiao-Qi Li |
| author_sort | Xue-Jiao Yang |
| collection | DOAJ |
| description | Lung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 65-year-old male of hemoptysis caused by a pulmonary artery pseudoaneurysm (PAP) after chemotherapy combined with tislelizumab for lung SCC. After confirmation with angiography, successful embolization was performed to occlude the pseudoaneurysm and proximal artery. To our knowledge, this is the first reported case of PAP formation after chemotherapy combined with tislelizumab for lung SCC. |
| format | Article |
| id | doaj-art-c76c693d0cf147f088f600335e11705b |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-c76c693d0cf147f088f600335e11705b2025-08-20T03:06:41ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-04-011210.3389/fmed.2025.15242481524248Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case reportXue-Jiao Yang0Yong-Juan Wu1Jing-Zhong Wang2Yu-Lan Zheng3Xiao-Qi Li4Department of Respiratory and Critical Care Medicine, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, ChinaDepartment of Interventional Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, ChinaDepartment of Interventional Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, ChinaDepartment of Respiratory and Critical Care Medicine, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, ChinaDepartment of Interventional Radiology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, ChinaLung squamous cell carcinoma (SCC) is a subtype of non-small cell lung cancer with high incidence and mortality rates. While chemotherapy and immune checkpoint inhibitors (ICIs) have become crucial treatment options for SCC, these may be associated with unforeseen complications. Here, we present a 65-year-old male of hemoptysis caused by a pulmonary artery pseudoaneurysm (PAP) after chemotherapy combined with tislelizumab for lung SCC. After confirmation with angiography, successful embolization was performed to occlude the pseudoaneurysm and proximal artery. To our knowledge, this is the first reported case of PAP formation after chemotherapy combined with tislelizumab for lung SCC.https://www.frontiersin.org/articles/10.3389/fmed.2025.1524248/fulllung squamous cell carcinomamassive hemoptysispulmonary artery pseudoaneurysmtislelizumabtumor necrosis |
| spellingShingle | Xue-Jiao Yang Yong-Juan Wu Jing-Zhong Wang Yu-Lan Zheng Xiao-Qi Li Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report Frontiers in Medicine lung squamous cell carcinoma massive hemoptysis pulmonary artery pseudoaneurysm tislelizumab tumor necrosis |
| title | Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report |
| title_full | Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report |
| title_fullStr | Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report |
| title_full_unstemmed | Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report |
| title_short | Pulmonary artery pseudoaneurysm-induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma: a case report |
| title_sort | pulmonary artery pseudoaneurysm induced massive hemoptysis after chemotherapy combined with tislelizumab for lung squamous cell carcinoma a case report |
| topic | lung squamous cell carcinoma massive hemoptysis pulmonary artery pseudoaneurysm tislelizumab tumor necrosis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1524248/full |
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