Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings
Background Sleep disorders have a negative impact on health, being associated with neurocognitive problems, cardiovascular diseases and obesity, influencing children's development and learning. Objective To assess the sleep pattern of people with Down syndrome (DS) and correlate chan...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2023-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768670 |
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| author | Marilia Rezende Callegari Kelly Brito dos Santos Barbara Valente de Oliveira Ana Rita Avelino Amorim Raquel Cymrot Silvana Maria Blascovi-Assis |
| author_facet | Marilia Rezende Callegari Kelly Brito dos Santos Barbara Valente de Oliveira Ana Rita Avelino Amorim Raquel Cymrot Silvana Maria Blascovi-Assis |
| author_sort | Marilia Rezende Callegari |
| collection | DOAJ |
| description | Background Sleep disorders have a negative impact on health, being associated with neurocognitive problems, cardiovascular diseases and obesity, influencing children's development and learning.
Objective To assess the sleep pattern of people with Down syndrome (DS) and correlate changes with functionality and behavior.
Methods A cross-sectional study was conducted to evaluate the sleep pattern in adults with DS > 18 years old. Twenty-two participants were assessed using the Pittsburgh Sleep Quality Index, the Functional Independence Measure and the Strengths and Difficulties Questionnaire, and the 11 who presented indications of disorders by the screening questionnaires were referred to polysomnography. Statistical tests were performed using a significance level of 5%, including sample normality tests and correlation tests (sleep and functionality).
Results Impairment in sleep architecture was found due to an increase in the rate of awakenings in 100% of the participants, a decrease in the number of slow waves, and a high prevalence of sleep disordered breathing (SDB), with higher averages in the Apnea and Hypopnea Index (AHI) in the group. There was a negative correlation between sleep quality and global functionality (p = 0.011) and the motor (p = 0.074), cognitive (p = 0.010), and personal care (p = 0.072) dimensions in the group. Global and hyperactivity behavior changes were related to worse sleep quality (p = 0.072; p = 0.015, respectively).
Conclusion There is an impairment in the sleep quality of adults with DS, with an increase in the rate of awakenings, a decrease in the number of slow waves, and a high prevalence of SDB affecting this population in the functional and behavioral aspects. |
| format | Article |
| id | doaj-art-c76203d5e4954b308d27bbad1035f94a |
| institution | OA Journals |
| issn | 0004-282X 1678-4227 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-c76203d5e4954b308d27bbad1035f94a2025-08-20T02:20:06ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria0004-282X1678-42272023-06-01810654455010.1055/s-0043-1768670Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findingsMarilia Rezende Callegari0Kelly Brito dos Santos1Barbara Valente de Oliveira2Ana Rita Avelino Amorim3Raquel Cymrot4Silvana Maria Blascovi-Assis5Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Universidade Presbiteriana Mackenzie, Centro de Ciências Biológicas e da Saúde, São Paulo SP, Brazil.Background Sleep disorders have a negative impact on health, being associated with neurocognitive problems, cardiovascular diseases and obesity, influencing children's development and learning. Objective To assess the sleep pattern of people with Down syndrome (DS) and correlate changes with functionality and behavior. Methods A cross-sectional study was conducted to evaluate the sleep pattern in adults with DS > 18 years old. Twenty-two participants were assessed using the Pittsburgh Sleep Quality Index, the Functional Independence Measure and the Strengths and Difficulties Questionnaire, and the 11 who presented indications of disorders by the screening questionnaires were referred to polysomnography. Statistical tests were performed using a significance level of 5%, including sample normality tests and correlation tests (sleep and functionality). Results Impairment in sleep architecture was found due to an increase in the rate of awakenings in 100% of the participants, a decrease in the number of slow waves, and a high prevalence of sleep disordered breathing (SDB), with higher averages in the Apnea and Hypopnea Index (AHI) in the group. There was a negative correlation between sleep quality and global functionality (p = 0.011) and the motor (p = 0.074), cognitive (p = 0.010), and personal care (p = 0.072) dimensions in the group. Global and hyperactivity behavior changes were related to worse sleep quality (p = 0.072; p = 0.015, respectively). Conclusion There is an impairment in the sleep quality of adults with DS, with an increase in the rate of awakenings, a decrease in the number of slow waves, and a high prevalence of SDB affecting this population in the functional and behavioral aspects.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768670down syndromesleepsleep wake disorderspolysomnographyphysical functional performance |
| spellingShingle | Marilia Rezende Callegari Kelly Brito dos Santos Barbara Valente de Oliveira Ana Rita Avelino Amorim Raquel Cymrot Silvana Maria Blascovi-Assis Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings Arquivos de Neuro-Psiquiatria down syndrome sleep sleep wake disorders polysomnography physical functional performance |
| title | Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings |
| title_full | Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings |
| title_fullStr | Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings |
| title_full_unstemmed | Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings |
| title_short | Sleep assessment in adults with Down syndrome: correlation between functionality and polysomnographic findings |
| title_sort | sleep assessment in adults with down syndrome correlation between functionality and polysomnographic findings |
| topic | down syndrome sleep sleep wake disorders polysomnography physical functional performance |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1768670 |
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