CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis

Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is the most common monogenic form of cerebral small-vessel disease characterised by recurrent strokes. Behavioural disturbance also presents in a significant proportion of subjects as neurotic spectru...

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Main Authors: Dheerendra Kumar Mishra, Aman Kishore, Vijay Niranjan
Format: Article
Language:English
Published: BMJ Publishing Group 2018-12-01
Series:General Psychiatry
Online Access:https://gpsych.bmj.com/content/31/3/e100017.full
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author Dheerendra Kumar Mishra
Aman Kishore
Vijay Niranjan
author_facet Dheerendra Kumar Mishra
Aman Kishore
Vijay Niranjan
author_sort Dheerendra Kumar Mishra
collection DOAJ
description Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is the most common monogenic form of cerebral small-vessel disease characterised by recurrent strokes. Behavioural disturbance also presents in a significant proportion of subjects as neurotic spectrum disorders and psychotic features are rarely reported. In this case report, we highlight a 32-year-old man with CADASIL syndrome, who had overt psychotic symptoms with neurological signs later on.
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institution DOAJ
issn 2517-729X
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publishDate 2018-12-01
publisher BMJ Publishing Group
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series General Psychiatry
spelling doaj-art-c75faf79342a4be79f77ad571cdb431e2025-08-20T02:49:55ZengBMJ Publishing GroupGeneral Psychiatry2517-729X2018-12-0131310.1136/gpsych-2018-100017CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosisDheerendra Kumar Mishra0Aman Kishore1Vijay Niranjan21 Department of Psychiatry, Shyam Shah Medical College Rewa, Rewa, Madhya Pradesh, India2 Masik Aarogyashala Gwalior, Indore, Madhya Pradesh, India3 Department of Psychiatry, M. G. M. Medical College Indore, Indore, Madhya Pradesh, IndiaCerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is the most common monogenic form of cerebral small-vessel disease characterised by recurrent strokes. Behavioural disturbance also presents in a significant proportion of subjects as neurotic spectrum disorders and psychotic features are rarely reported. In this case report, we highlight a 32-year-old man with CADASIL syndrome, who had overt psychotic symptoms with neurological signs later on.https://gpsych.bmj.com/content/31/3/e100017.full
spellingShingle Dheerendra Kumar Mishra
Aman Kishore
Vijay Niranjan
CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
General Psychiatry
title CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
title_full CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
title_fullStr CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
title_full_unstemmed CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
title_short CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) presenting as psychosis
title_sort cadasil syndrome cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy presenting as psychosis
url https://gpsych.bmj.com/content/31/3/e100017.full
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AT amankishore cadasilsyndromecerebralautosomaldominantarteriopathywithsubcorticalinfarctsandleukoencephalopathypresentingaspsychosis
AT vijayniranjan cadasilsyndromecerebralautosomaldominantarteriopathywithsubcorticalinfarctsandleukoencephalopathypresentingaspsychosis