Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Abstract New treatment strategies are urgently needed for patients with advanced cervical cancer (CC). Here, a synergistic anti‐CC effect of a novel combinatorial immunotherapy with adoptively transferred autologous Vγ9Vδ2 T cells and αβ T cells is shown. The pivotal role of both circulating and tum...

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Main Authors: Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
antigen presentation
BTN3A1
cervical cancer
immunotherapy
Vγ9Vδ2 T cell
α
Online Access:https://doi.org/10.1002/advs.202401230
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